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Loss of HtrA1 serine protease induces synthetic modulation of aortic vascular smooth muscle cells
Homozygous mutations of human HTRA1 cause cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL). HtrA1(-/-) mice were examined for arterial abnormalities. Although their cerebral arteries were normal, the thoracic aorta was affected in HtrA1(-/-) mice....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955505/ https://www.ncbi.nlm.nih.gov/pubmed/29768431 http://dx.doi.org/10.1371/journal.pone.0196628 |