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Treatment with specific soluble factors promotes the functional maturation of transcription factor-mediated, pancreatic transdifferentiated cells
Pancreatic lineage-specific transcription factors (TFs) display instructive roles in converting adult cells to endocrine pancreatic cells through a process known as transdifferentiation. However, little is known about potential factors capable of accelerating transdifferentiation following transduct...
Autores principales: | Motoyama, Hiroaki, Kobayashi, Akira, Yokoyama, Takahide, Shimizu, Akira, Sakai, Hiroshi, Notake, Tsuyoshi, Fukushima, Kentaro, Miyagawa, Shin-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955553/ https://www.ncbi.nlm.nih.gov/pubmed/29768476 http://dx.doi.org/10.1371/journal.pone.0197175 |
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