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Choroidal thickness in normal Indian subjects using Swept source optical coherence tomography
AIM: To determine choroidal thickness in healthy Indian subjects using Swept source optical coherence tomography (SS-OCT). METHODS: In this prospective, observational, cross-sectional study; healthy Indian subjects (n = 230) with no history of ocular and/or systemic disorders were enrolled in the st...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955571/ https://www.ncbi.nlm.nih.gov/pubmed/29768485 http://dx.doi.org/10.1371/journal.pone.0197457 |
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author | Akhtar, Zeeshan Rishi, Pukhraj Srikanth, Ramasubramanian Rishi, Ekta Bhende, Muna Raman, Rajiv |
author_facet | Akhtar, Zeeshan Rishi, Pukhraj Srikanth, Ramasubramanian Rishi, Ekta Bhende, Muna Raman, Rajiv |
author_sort | Akhtar, Zeeshan |
collection | PubMed |
description | AIM: To determine choroidal thickness in healthy Indian subjects using Swept source optical coherence tomography (SS-OCT). METHODS: In this prospective, observational, cross-sectional study; healthy Indian subjects (n = 230) with no history of ocular and/or systemic disorders were enrolled in the study. Choroidal thickness was measured for 230 eyes using SS-OCT. Subjects were divided into six age groups. Main outcome measures were subfoveal choroidal thickness (SFCT) and macular choroidal thickness (MCT) up to 3 mm at 500-micron interval from the fovea was measured in eight different quadrants. RESULTS: The mean SFCT was 307±79 μm and mean MCT was 285±75 μm. No difference in the choroidal thickness was found among genders. Mean SFCT of the different age groups was 327±68 μm (12–18 years), 364±70 μm (18.1–30 years), 321±78 μm (30.1–40 years), 304±79 μm (40.1–50 years), 283±69 μm (50.1–60 years) and 262±72μm (above 60 years; p <0.001; One way ANOVA). Mean macular choroidal thickness was 305±60 μm, 342±61 μm, 306±72 μm, 282±79 μm, 261±66 μm, 238±68μm respectively (p<0.001; one way ANOVA). A significant weak negative correlation was found between age with SFCT (r = -0.368, p<0.001) and MCT (r = -0.40, p<0.001). No significant correlation was found with refractive error, axial length and ocular perfusion pressure. CONCLUSION: This study showed that mean SFCT and MCT was 307±79μm and 285±75 μm, respectively, among healthy Indian subjects. Mean CT was found to decrease with age, although there was no difference in CT between genders. |
format | Online Article Text |
id | pubmed-5955571 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-59555712018-05-25 Choroidal thickness in normal Indian subjects using Swept source optical coherence tomography Akhtar, Zeeshan Rishi, Pukhraj Srikanth, Ramasubramanian Rishi, Ekta Bhende, Muna Raman, Rajiv PLoS One Research Article AIM: To determine choroidal thickness in healthy Indian subjects using Swept source optical coherence tomography (SS-OCT). METHODS: In this prospective, observational, cross-sectional study; healthy Indian subjects (n = 230) with no history of ocular and/or systemic disorders were enrolled in the study. Choroidal thickness was measured for 230 eyes using SS-OCT. Subjects were divided into six age groups. Main outcome measures were subfoveal choroidal thickness (SFCT) and macular choroidal thickness (MCT) up to 3 mm at 500-micron interval from the fovea was measured in eight different quadrants. RESULTS: The mean SFCT was 307±79 μm and mean MCT was 285±75 μm. No difference in the choroidal thickness was found among genders. Mean SFCT of the different age groups was 327±68 μm (12–18 years), 364±70 μm (18.1–30 years), 321±78 μm (30.1–40 years), 304±79 μm (40.1–50 years), 283±69 μm (50.1–60 years) and 262±72μm (above 60 years; p <0.001; One way ANOVA). Mean macular choroidal thickness was 305±60 μm, 342±61 μm, 306±72 μm, 282±79 μm, 261±66 μm, 238±68μm respectively (p<0.001; one way ANOVA). A significant weak negative correlation was found between age with SFCT (r = -0.368, p<0.001) and MCT (r = -0.40, p<0.001). No significant correlation was found with refractive error, axial length and ocular perfusion pressure. CONCLUSION: This study showed that mean SFCT and MCT was 307±79μm and 285±75 μm, respectively, among healthy Indian subjects. Mean CT was found to decrease with age, although there was no difference in CT between genders. Public Library of Science 2018-05-16 /pmc/articles/PMC5955571/ /pubmed/29768485 http://dx.doi.org/10.1371/journal.pone.0197457 Text en © 2018 Akhtar et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Akhtar, Zeeshan Rishi, Pukhraj Srikanth, Ramasubramanian Rishi, Ekta Bhende, Muna Raman, Rajiv Choroidal thickness in normal Indian subjects using Swept source optical coherence tomography |
title | Choroidal thickness in normal Indian subjects using Swept source optical coherence tomography |
title_full | Choroidal thickness in normal Indian subjects using Swept source optical coherence tomography |
title_fullStr | Choroidal thickness in normal Indian subjects using Swept source optical coherence tomography |
title_full_unstemmed | Choroidal thickness in normal Indian subjects using Swept source optical coherence tomography |
title_short | Choroidal thickness in normal Indian subjects using Swept source optical coherence tomography |
title_sort | choroidal thickness in normal indian subjects using swept source optical coherence tomography |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955571/ https://www.ncbi.nlm.nih.gov/pubmed/29768485 http://dx.doi.org/10.1371/journal.pone.0197457 |
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