Production and rearing of germ-free X-SCID pigs

Pigs with X-linked severe combined immunodeficiency (X-SCID) caused by a mutation of the interleukin-2 receptor gamma chain gene (IL2RG) are of value for a wide range of studies. However, they do not survive longer than 8 weeks because of their susceptibility to infections. To allow longer survival...

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Detalles Bibliográficos
Autores principales: Hara, Hiromasa, Shibata, Hiroaki, Nakano, Kazuaki, Abe, Tomoyuki, Uosaki, Hideki, Ohnuki, Takahiro, Hishikawa, Shuji, Kunita, Satoshi, Watanabe, Masahito, Nureki, Osamu, Nagashima, Hiroshi, Hanazono, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2017
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955745/
https://www.ncbi.nlm.nih.gov/pubmed/29162766
http://dx.doi.org/10.1538/expanim.17-0095

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