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modCHIMERA: a novel murine closed-head model of moderate traumatic brain injury

Traumatic brain injury is a major source of global disability and mortality. Preclinical TBI models are a crucial component of therapeutic investigation. We report a tunable, monitored model of murine non-surgical, diffuse closed-head injury—modCHIMERA—characterized by impact as well as linear and r...

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Detalles Bibliográficos
Autores principales: Sauerbeck, A. D., Fanizzi, C., Kim, J. H., Gangolli, M., Bayly, P. V., Wellington, C. L., Brody, D. L., Kummer, T. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955903/
https://www.ncbi.nlm.nih.gov/pubmed/29769541
http://dx.doi.org/10.1038/s41598-018-25737-6