Changes in L4/5 Intervertebral Foramen Bony Morphology with Age
The purpose of this study was to explore the morphological changes in L4/5 intervertebral foramen with age using a digital method. The closed boundaries of the intervertebral foramen (IGES) in different sagittal slices (inside, middle and outside) were obtained from Mimics, and then imported to a cu...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955929/ https://www.ncbi.nlm.nih.gov/pubmed/29769656 http://dx.doi.org/10.1038/s41598-018-26077-1 |
_version_ | 1783323791207694336 |
---|---|
author | Yan, Shuaifeng Wang, Kai Zhang, Yunfan Guo, Song Zhang, Yan Tan, Jun |
author_facet | Yan, Shuaifeng Wang, Kai Zhang, Yunfan Guo, Song Zhang, Yan Tan, Jun |
author_sort | Yan, Shuaifeng |
collection | PubMed |
description | The purpose of this study was to explore the morphological changes in L4/5 intervertebral foramen with age using a digital method. The closed boundaries of the intervertebral foramen (IGES) in different sagittal slices (inside, middle and outside) were obtained from Mimics, and then imported to a custom-written program, which provided quantitative distance between the nerve root and the closed curves. The quantitative information of each age group was used to produce radar chart and line chart for morphological and statistical analyses. Overall, the intervertebral foramen changes mainly occurred in the inner part from middle age to old age. The foraminal height decreased with age in the inside sagittal slice, while no significant difference was found in the middle sagittal slice or the outside sagittal slice. The foraminal width showed no decrease in each age group or each sagittal plane. The present study described foraminal geometry of asymptomatic males in different sagittal slices with age. This information enhances the knowledge of anatomical changes in intervertebral foramen with age, which provides better understanding of the pathology of intervertebral foramen diseases. |
format | Online Article Text |
id | pubmed-5955929 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-59559292018-05-21 Changes in L4/5 Intervertebral Foramen Bony Morphology with Age Yan, Shuaifeng Wang, Kai Zhang, Yunfan Guo, Song Zhang, Yan Tan, Jun Sci Rep Article The purpose of this study was to explore the morphological changes in L4/5 intervertebral foramen with age using a digital method. The closed boundaries of the intervertebral foramen (IGES) in different sagittal slices (inside, middle and outside) were obtained from Mimics, and then imported to a custom-written program, which provided quantitative distance between the nerve root and the closed curves. The quantitative information of each age group was used to produce radar chart and line chart for morphological and statistical analyses. Overall, the intervertebral foramen changes mainly occurred in the inner part from middle age to old age. The foraminal height decreased with age in the inside sagittal slice, while no significant difference was found in the middle sagittal slice or the outside sagittal slice. The foraminal width showed no decrease in each age group or each sagittal plane. The present study described foraminal geometry of asymptomatic males in different sagittal slices with age. This information enhances the knowledge of anatomical changes in intervertebral foramen with age, which provides better understanding of the pathology of intervertebral foramen diseases. Nature Publishing Group UK 2018-05-16 /pmc/articles/PMC5955929/ /pubmed/29769656 http://dx.doi.org/10.1038/s41598-018-26077-1 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Yan, Shuaifeng Wang, Kai Zhang, Yunfan Guo, Song Zhang, Yan Tan, Jun Changes in L4/5 Intervertebral Foramen Bony Morphology with Age |
title | Changes in L4/5 Intervertebral Foramen Bony Morphology with Age |
title_full | Changes in L4/5 Intervertebral Foramen Bony Morphology with Age |
title_fullStr | Changes in L4/5 Intervertebral Foramen Bony Morphology with Age |
title_full_unstemmed | Changes in L4/5 Intervertebral Foramen Bony Morphology with Age |
title_short | Changes in L4/5 Intervertebral Foramen Bony Morphology with Age |
title_sort | changes in l4/5 intervertebral foramen bony morphology with age |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955929/ https://www.ncbi.nlm.nih.gov/pubmed/29769656 http://dx.doi.org/10.1038/s41598-018-26077-1 |
work_keys_str_mv | AT yanshuaifeng changesinl45intervertebralforamenbonymorphologywithage AT wangkai changesinl45intervertebralforamenbonymorphologywithage AT zhangyunfan changesinl45intervertebralforamenbonymorphologywithage AT guosong changesinl45intervertebralforamenbonymorphologywithage AT zhangyan changesinl45intervertebralforamenbonymorphologywithage AT tanjun changesinl45intervertebralforamenbonymorphologywithage |