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Depletion of microglia augments the dopaminergic neurotoxicity of MPTP

The activation of microglia and the various substances they produce have been linked to the pathologic development of Parkinson’s disease (PD), but the precise role of microglia in PD remains to be defined. The survival of microglia depends on colony-stimulating factor 1 receptor (CSF1R) signaling,...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoxia, Ren, Honglei, Wood, Kristofer, Li, Minshu, Qiu, Shenfeng, Shi, Fu-Dong, Ma, Cungen, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956250/
https://www.ncbi.nlm.nih.gov/pubmed/29401614
http://dx.doi.org/10.1096/fj.201700833RR