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Embryos, Clones, and Stem Cells: A Scientific Primer

This article is intended to give the nonspecialist an insight into the nuances of “clones”, cloning, and stem cells. It distinguishes embryonic and adult stem cells, their normal function in the organism, their origin, and how they are recovered to produce stem cell lines in culture. As background,...

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Autor principal: Tweedell, Kenyon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956295/
https://www.ncbi.nlm.nih.gov/pubmed/15349510
http://dx.doi.org/10.1100/tsw.2004.121
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author Tweedell, Kenyon S.
author_facet Tweedell, Kenyon S.
author_sort Tweedell, Kenyon S.
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description This article is intended to give the nonspecialist an insight into the nuances of “clones”, cloning, and stem cells. It distinguishes embryonic and adult stem cells, their normal function in the organism, their origin, and how they are recovered to produce stem cell lines in culture. As background, the fundamental processes of embryo development are reviewed and defined, since the manipulation of stem cell lines into desired specialized cells employs many of the same events. Stem cells are defined and characterized and shown how they function in the intact organism during early development and later during cell regeneration in the adult. The complexity of stem cell recovery and their manipulation into specific cells and tissue is illustrated by reviewing current experimentation on both embryonic and adult stem cells in animals and limited research on human stem cell lines. The current and projected use of stem cells for human diseases and repair, along with the expanding methodology for the recovery of human embryonic stem cells, is described. An assessment on the use of human embryonic stem cells is considered from ethical, legal, religious, and political viewpoints.
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spelling pubmed-59562952018-06-03 Embryos, Clones, and Stem Cells: A Scientific Primer Tweedell, Kenyon S. ScientificWorldJournal Review Article This article is intended to give the nonspecialist an insight into the nuances of “clones”, cloning, and stem cells. It distinguishes embryonic and adult stem cells, their normal function in the organism, their origin, and how they are recovered to produce stem cell lines in culture. As background, the fundamental processes of embryo development are reviewed and defined, since the manipulation of stem cell lines into desired specialized cells employs many of the same events. Stem cells are defined and characterized and shown how they function in the intact organism during early development and later during cell regeneration in the adult. The complexity of stem cell recovery and their manipulation into specific cells and tissue is illustrated by reviewing current experimentation on both embryonic and adult stem cells in animals and limited research on human stem cell lines. The current and projected use of stem cells for human diseases and repair, along with the expanding methodology for the recovery of human embryonic stem cells, is described. An assessment on the use of human embryonic stem cells is considered from ethical, legal, religious, and political viewpoints. TheScientificWorldJOURNAL 2004-08-18 /pmc/articles/PMC5956295/ /pubmed/15349510 http://dx.doi.org/10.1100/tsw.2004.121 Text en Copyright © 2004 Kenyon S. Tweedell. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Tweedell, Kenyon S.
Embryos, Clones, and Stem Cells: A Scientific Primer
title Embryos, Clones, and Stem Cells: A Scientific Primer
title_full Embryos, Clones, and Stem Cells: A Scientific Primer
title_fullStr Embryos, Clones, and Stem Cells: A Scientific Primer
title_full_unstemmed Embryos, Clones, and Stem Cells: A Scientific Primer
title_short Embryos, Clones, and Stem Cells: A Scientific Primer
title_sort embryos, clones, and stem cells: a scientific primer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956295/
https://www.ncbi.nlm.nih.gov/pubmed/15349510
http://dx.doi.org/10.1100/tsw.2004.121
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