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Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects
Intrauterine neural tube defects, meningomyelocele, and diastematomyelia are developmental errors at different stages of the closure of the neural tube. The familial aggregation of these neural tube defects is not previously reported in the literature and should make one think about a common embryog...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956507/ https://www.ncbi.nlm.nih.gov/pubmed/15452650 http://dx.doi.org/10.1100/tsw.2004.140 |
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author | Kanbur, Nuray Öksüz Güner, Pınar Derman, Orhan Akalan, Nejat Cila, Ayşenur Kutluk, Tezer |
author_facet | Kanbur, Nuray Öksüz Güner, Pınar Derman, Orhan Akalan, Nejat Cila, Ayşenur Kutluk, Tezer |
author_sort | Kanbur, Nuray Öksüz |
collection | PubMed |
description | Intrauterine neural tube defects, meningomyelocele, and diastematomyelia are developmental errors at different stages of the closure of the neural tube. The familial aggregation of these neural tube defects is not previously reported in the literature and should make one think about a common embryogenesis and a possible common mechanism of etiopathogenesis leading to anomalies at different stages of this embryogenesis. This paper presents a 12-year-old Turkish boy with diastematomyelia who was suspected with a demonstrative dermatologic finding without any neurologic sign and diagnosed with magnetic resonance imaging (MRI). He has a positive family history of a stillbirth with neural tube defect, an exitus with meningomyelocele, and an epileptic child in his female siblings. |
format | Online Article Text |
id | pubmed-5956507 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | TheScientificWorldJOURNAL |
record_format | MEDLINE/PubMed |
spelling | pubmed-59565072018-06-03 Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects Kanbur, Nuray Öksüz Güner, Pınar Derman, Orhan Akalan, Nejat Cila, Ayşenur Kutluk, Tezer ScientificWorldJournal Case Study Intrauterine neural tube defects, meningomyelocele, and diastematomyelia are developmental errors at different stages of the closure of the neural tube. The familial aggregation of these neural tube defects is not previously reported in the literature and should make one think about a common embryogenesis and a possible common mechanism of etiopathogenesis leading to anomalies at different stages of this embryogenesis. This paper presents a 12-year-old Turkish boy with diastematomyelia who was suspected with a demonstrative dermatologic finding without any neurologic sign and diagnosed with magnetic resonance imaging (MRI). He has a positive family history of a stillbirth with neural tube defect, an exitus with meningomyelocele, and an epileptic child in his female siblings. TheScientificWorldJOURNAL 2004-09-21 /pmc/articles/PMC5956507/ /pubmed/15452650 http://dx.doi.org/10.1100/tsw.2004.140 Text en Copyright © 2004 Nuray Öksüz Kanbur et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Study Kanbur, Nuray Öksüz Güner, Pınar Derman, Orhan Akalan, Nejat Cila, Ayşenur Kutluk, Tezer Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects |
title | Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects |
title_full | Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects |
title_fullStr | Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects |
title_full_unstemmed | Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects |
title_short | Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects |
title_sort | diastematomyelia: a case with familial aggregation of neural tube defects |
topic | Case Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956507/ https://www.ncbi.nlm.nih.gov/pubmed/15452650 http://dx.doi.org/10.1100/tsw.2004.140 |
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