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Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects

Intrauterine neural tube defects, meningomyelocele, and diastematomyelia are developmental errors at different stages of the closure of the neural tube. The familial aggregation of these neural tube defects is not previously reported in the literature and should make one think about a common embryog...

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Autores principales: Kanbur, Nuray Öksüz, Güner, Pınar, Derman, Orhan, Akalan, Nejat, Cila, Ayşenur, Kutluk, Tezer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956507/
https://www.ncbi.nlm.nih.gov/pubmed/15452650
http://dx.doi.org/10.1100/tsw.2004.140
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author Kanbur, Nuray Öksüz
Güner, Pınar
Derman, Orhan
Akalan, Nejat
Cila, Ayşenur
Kutluk, Tezer
author_facet Kanbur, Nuray Öksüz
Güner, Pınar
Derman, Orhan
Akalan, Nejat
Cila, Ayşenur
Kutluk, Tezer
author_sort Kanbur, Nuray Öksüz
collection PubMed
description Intrauterine neural tube defects, meningomyelocele, and diastematomyelia are developmental errors at different stages of the closure of the neural tube. The familial aggregation of these neural tube defects is not previously reported in the literature and should make one think about a common embryogenesis and a possible common mechanism of etiopathogenesis leading to anomalies at different stages of this embryogenesis. This paper presents a 12-year-old Turkish boy with diastematomyelia who was suspected with a demonstrative dermatologic finding without any neurologic sign and diagnosed with magnetic resonance imaging (MRI). He has a positive family history of a stillbirth with neural tube defect, an exitus with meningomyelocele, and an epileptic child in his female siblings.
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spelling pubmed-59565072018-06-03 Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects Kanbur, Nuray Öksüz Güner, Pınar Derman, Orhan Akalan, Nejat Cila, Ayşenur Kutluk, Tezer ScientificWorldJournal Case Study Intrauterine neural tube defects, meningomyelocele, and diastematomyelia are developmental errors at different stages of the closure of the neural tube. The familial aggregation of these neural tube defects is not previously reported in the literature and should make one think about a common embryogenesis and a possible common mechanism of etiopathogenesis leading to anomalies at different stages of this embryogenesis. This paper presents a 12-year-old Turkish boy with diastematomyelia who was suspected with a demonstrative dermatologic finding without any neurologic sign and diagnosed with magnetic resonance imaging (MRI). He has a positive family history of a stillbirth with neural tube defect, an exitus with meningomyelocele, and an epileptic child in his female siblings. TheScientificWorldJOURNAL 2004-09-21 /pmc/articles/PMC5956507/ /pubmed/15452650 http://dx.doi.org/10.1100/tsw.2004.140 Text en Copyright © 2004 Nuray Öksüz Kanbur et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Study
Kanbur, Nuray Öksüz
Güner, Pınar
Derman, Orhan
Akalan, Nejat
Cila, Ayşenur
Kutluk, Tezer
Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects
title Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects
title_full Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects
title_fullStr Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects
title_full_unstemmed Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects
title_short Diastematomyelia: A Case with Familial Aggregation of Neural Tube Defects
title_sort diastematomyelia: a case with familial aggregation of neural tube defects
topic Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956507/
https://www.ncbi.nlm.nih.gov/pubmed/15452650
http://dx.doi.org/10.1100/tsw.2004.140
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