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Circulating tumour DNA for monitoring colorectal cancer—a prospective cohort study to assess relationship to tissue methylation, cancer characteristics and surgical resection

BACKGROUND: Cell-free circulating tumour-derived DNA (ctDNA) can be detected by testing for methylated BCAT1 and IKZF1 DNA, which has proven sensitivity for colorectal cancer (CRC). A prospective correlative biomarker study between presence of methylated BCAT1 and IKZF1 in tissue and blood was condu...

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Detalles Bibliográficos
Autores principales:	Symonds, Erin L., Pedersen, Susanne K., Murray, David H., Jedi, Maher, Byrne, Susan E., Rabbitt, Philippa, Baker, Rohan T., Bastin, Dawn, Young, Graeme P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956533/ https://www.ncbi.nlm.nih.gov/pubmed/29796114 http://dx.doi.org/10.1186/s13148-018-0500-5

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