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Orbital implant exposure after Acanthamoeba panophthalmitis
PURPOSE: Acanthamoeba is a protozoa that can lead to severe ocular disease and sequelae. Although intraocular Acanthamoeba infection is rare, the following case demonstrates an unusual presentation of recurrent Acanthamoeba infection in a 30 year old contact lens wearing male. OBSERVATIONS: After pr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956657/ https://www.ncbi.nlm.nih.gov/pubmed/29780912 http://dx.doi.org/10.1016/j.ajoc.2018.01.043 |
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author | Baker, Meredith S. Maltry, Amanda C. Syed, Nasreen A. Allen, Richard C. |
author_facet | Baker, Meredith S. Maltry, Amanda C. Syed, Nasreen A. Allen, Richard C. |
author_sort | Baker, Meredith S. |
collection | PubMed |
description | PURPOSE: Acanthamoeba is a protozoa that can lead to severe ocular disease and sequelae. Although intraocular Acanthamoeba infection is rare, the following case demonstrates an unusual presentation of recurrent Acanthamoeba infection in a 30 year old contact lens wearing male. OBSERVATIONS: After presenting with recurrent Acanthamoeba keratitis and undergoing various treatments, the patient developed nodular scleritis, which evolved into panophthalmitis, and ultimately, required enucleation. Eight months post-operatively, the patient developed orbital implant exposure secondary to persistent Acanthamoeba infection and underwent removal of the implant and aggressive, systemic treatment involving a multispecialty care team. He then underwent placement of a dermis fat graft and had no signs of persistent infection at the time of last follow-up, which was 24 months after placement of the dermis fat graft. CONCLUSIONS: and Importance: To the authors' knowledge, this is the first known case of Acanthamoeba infection causing orbital implant exposure. Persistent infection should be considered in Acanthamoeba patients who have undergone enucleation and have orbital implant exposure. Better knowledge regarding the pathogenesis and extracorneal complications of this challenging disease may improve patient care and outcomes. |
format | Online Article Text |
id | pubmed-5956657 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-59566572018-05-18 Orbital implant exposure after Acanthamoeba panophthalmitis Baker, Meredith S. Maltry, Amanda C. Syed, Nasreen A. Allen, Richard C. Am J Ophthalmol Case Rep Brief report PURPOSE: Acanthamoeba is a protozoa that can lead to severe ocular disease and sequelae. Although intraocular Acanthamoeba infection is rare, the following case demonstrates an unusual presentation of recurrent Acanthamoeba infection in a 30 year old contact lens wearing male. OBSERVATIONS: After presenting with recurrent Acanthamoeba keratitis and undergoing various treatments, the patient developed nodular scleritis, which evolved into panophthalmitis, and ultimately, required enucleation. Eight months post-operatively, the patient developed orbital implant exposure secondary to persistent Acanthamoeba infection and underwent removal of the implant and aggressive, systemic treatment involving a multispecialty care team. He then underwent placement of a dermis fat graft and had no signs of persistent infection at the time of last follow-up, which was 24 months after placement of the dermis fat graft. CONCLUSIONS: and Importance: To the authors' knowledge, this is the first known case of Acanthamoeba infection causing orbital implant exposure. Persistent infection should be considered in Acanthamoeba patients who have undergone enucleation and have orbital implant exposure. Better knowledge regarding the pathogenesis and extracorneal complications of this challenging disease may improve patient care and outcomes. Elsevier 2018-01-31 /pmc/articles/PMC5956657/ /pubmed/29780912 http://dx.doi.org/10.1016/j.ajoc.2018.01.043 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Brief report Baker, Meredith S. Maltry, Amanda C. Syed, Nasreen A. Allen, Richard C. Orbital implant exposure after Acanthamoeba panophthalmitis |
title | Orbital implant exposure after Acanthamoeba panophthalmitis |
title_full | Orbital implant exposure after Acanthamoeba panophthalmitis |
title_fullStr | Orbital implant exposure after Acanthamoeba panophthalmitis |
title_full_unstemmed | Orbital implant exposure after Acanthamoeba panophthalmitis |
title_short | Orbital implant exposure after Acanthamoeba panophthalmitis |
title_sort | orbital implant exposure after acanthamoeba panophthalmitis |
topic | Brief report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956657/ https://www.ncbi.nlm.nih.gov/pubmed/29780912 http://dx.doi.org/10.1016/j.ajoc.2018.01.043 |
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