Altered Cerebellar Short-Term Plasticity but No Change in Postsynaptic AMPA-Type Glutamate Receptors in a Mouse Model of Juvenile Batten Disease

Juvenile Batten disease is the most common progressive neurodegenerative disorder of childhood. It is associated with mutations in the CLN3 gene, causing loss of function of CLN3 protein and degeneration of cerebellar and retinal neurons. It has been proposed that changes in granule cell AMPA-type g...

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Detalles Bibliográficos
Autores principales: Studniarczyk, Dorota, Needham, Elizabeth L., Mitchison, Hannah M., Farrant, Mark, Cull-Candy, Stuart G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956745/
https://www.ncbi.nlm.nih.gov/pubmed/29780879
http://dx.doi.org/10.1523/ENEURO.0387-17.2018

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