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Risk factors for incident falls in older men and women: the English longitudinal study of ageing

BACKGROUND: Falls are a major cause of disability and death in older people, particularly women. Cross-sectional surveys suggest that some risk factors associated with a history of falls may be sex-specific, but whether risk factors for incident falls differ between the sexes is unclear. We investig...

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Autores principales: Gale, Catharine R., Westbury, Leo D., Cooper, Cyrus, Dennison, Elaine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956831/
https://www.ncbi.nlm.nih.gov/pubmed/29769023
http://dx.doi.org/10.1186/s12877-018-0806-3
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author Gale, Catharine R.
Westbury, Leo D.
Cooper, Cyrus
Dennison, Elaine M.
author_facet Gale, Catharine R.
Westbury, Leo D.
Cooper, Cyrus
Dennison, Elaine M.
author_sort Gale, Catharine R.
collection PubMed
description BACKGROUND: Falls are a major cause of disability and death in older people, particularly women. Cross-sectional surveys suggest that some risk factors associated with a history of falls may be sex-specific, but whether risk factors for incident falls differ between the sexes is unclear. We investigated whether risk factors for incident falls differ between men and women. METHODS: Participants were 3298 people aged ≥60 who took part in the Waves 4–6 surveys of the English Longitudinal Study of Ageing. At Wave 4, they provided information about sociodemographic, lifestyle, behavioural and medical factors and had their physical and cognitive function assessed. Data on incident falls during the four-year follow-up period was collected from them at Waves 5 and 6. Poisson regression with robust variance estimation was used to derive relative risks (RR) for the association between baseline characteristics and incident falls. RESULTS: In multivariable-adjusted models that also controlled for history of falls, older age was the only factor associated with increased risk of incident falls in both sexes. Some factors were only predictive of falls in one sex, namely more depressive symptoms (RR (95% CI) 1.03 (1.01,1.06)), incontinence (1.12 (1.00,1.24)) and never having married in women (1.26 (1.03,1.53)), and greater comorbidity (1.04 (1.00,1.08)), higher levels of pain (1.10 (1.04,1.17) and poorer balance, as indicated by inability to attempt a full-tandem stand, (1.23 (1.04,1.47)) in men. Of these, only the relationships between pain, balance and comorbidity and falls risk differed significantly by sex. CONCLUSIONS: There were some differences between the sexes in risk factors for incident falls. Our observation that associations between pain, balance and comorbidity and incident falls risk varied by sex needs further investigation in other cohorts.
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spelling pubmed-59568312018-05-24 Risk factors for incident falls in older men and women: the English longitudinal study of ageing Gale, Catharine R. Westbury, Leo D. Cooper, Cyrus Dennison, Elaine M. BMC Geriatr Research Article BACKGROUND: Falls are a major cause of disability and death in older people, particularly women. Cross-sectional surveys suggest that some risk factors associated with a history of falls may be sex-specific, but whether risk factors for incident falls differ between the sexes is unclear. We investigated whether risk factors for incident falls differ between men and women. METHODS: Participants were 3298 people aged ≥60 who took part in the Waves 4–6 surveys of the English Longitudinal Study of Ageing. At Wave 4, they provided information about sociodemographic, lifestyle, behavioural and medical factors and had their physical and cognitive function assessed. Data on incident falls during the four-year follow-up period was collected from them at Waves 5 and 6. Poisson regression with robust variance estimation was used to derive relative risks (RR) for the association between baseline characteristics and incident falls. RESULTS: In multivariable-adjusted models that also controlled for history of falls, older age was the only factor associated with increased risk of incident falls in both sexes. Some factors were only predictive of falls in one sex, namely more depressive symptoms (RR (95% CI) 1.03 (1.01,1.06)), incontinence (1.12 (1.00,1.24)) and never having married in women (1.26 (1.03,1.53)), and greater comorbidity (1.04 (1.00,1.08)), higher levels of pain (1.10 (1.04,1.17) and poorer balance, as indicated by inability to attempt a full-tandem stand, (1.23 (1.04,1.47)) in men. Of these, only the relationships between pain, balance and comorbidity and falls risk differed significantly by sex. CONCLUSIONS: There were some differences between the sexes in risk factors for incident falls. Our observation that associations between pain, balance and comorbidity and incident falls risk varied by sex needs further investigation in other cohorts. BioMed Central 2018-05-16 /pmc/articles/PMC5956831/ /pubmed/29769023 http://dx.doi.org/10.1186/s12877-018-0806-3 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Gale, Catharine R.
Westbury, Leo D.
Cooper, Cyrus
Dennison, Elaine M.
Risk factors for incident falls in older men and women: the English longitudinal study of ageing
title Risk factors for incident falls in older men and women: the English longitudinal study of ageing
title_full Risk factors for incident falls in older men and women: the English longitudinal study of ageing
title_fullStr Risk factors for incident falls in older men and women: the English longitudinal study of ageing
title_full_unstemmed Risk factors for incident falls in older men and women: the English longitudinal study of ageing
title_short Risk factors for incident falls in older men and women: the English longitudinal study of ageing
title_sort risk factors for incident falls in older men and women: the english longitudinal study of ageing
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956831/
https://www.ncbi.nlm.nih.gov/pubmed/29769023
http://dx.doi.org/10.1186/s12877-018-0806-3
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