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Intense Pulsed Light Therapy for Acne-induced Post-inflammatory Erythema

BACKGROUND: Intense pulsed light (IPL) is a comparatively new system of practice in treating acne-induced post inflammatory erythema (PIE) which is a difficult condition to treat, and variations exist in the results from published studies with insufficient or limited scientific evidence of IPL on In...

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Autores principales: Mathew, Minu L., Karthik, R., Mallikarjun, M., Bhute, Soumya, Varghese, Aiswarya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956861/
https://www.ncbi.nlm.nih.gov/pubmed/29854634
http://dx.doi.org/10.4103/idoj.IDOJ_306_17
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author Mathew, Minu L.
Karthik, R.
Mallikarjun, M.
Bhute, Soumya
Varghese, Aiswarya
author_facet Mathew, Minu L.
Karthik, R.
Mallikarjun, M.
Bhute, Soumya
Varghese, Aiswarya
author_sort Mathew, Minu L.
collection PubMed
description BACKGROUND: Intense pulsed light (IPL) is a comparatively new system of practice in treating acne-induced post inflammatory erythema (PIE) which is a difficult condition to treat, and variations exist in the results from published studies with insufficient or limited scientific evidence of IPL on Indian skin. AIM: To study the efficacy of IPL in the treatment of acne-induced PIE and to document adverse effects of the procedure. SETTINGS AND DESIGN: A hospital-based retrospective observational study on 33 patients with acne-induced PIE who completed treatment with IPL during the time period of July 2015 to June 2017. PATIENTS AND METHODS: All 33 patients were treated with vascular mode of IPL using 560-nm filter every 3 weeks for three to six sessions. Grading of PIE was done by Clinician Erythema Severity Score, and the objective parameters were assessed statistically for improvement using photographs. Adverse effects were noted and followed up. STATISTICAL ANALYSIS: Wilcoxon sign rank test and Pearson's correlation. RESULTS: There was statistically significant reduction in mean erythema score from 2.57 ± 0.66 to 1.21 ± 0.48 following IPL (Z = −5.295, P < 0.001—Wilcoxon sign rank test). Excellent improvement was noted in 11 (33.33%), good in 15 (45.45%), fair in 4 (12.12%), and poor in 3 (9.09%), and the results were consistent on follow-up. Adverse effects included erythema, hyperpigmentation, and hypopigmentation which were all transient and resolved completely in all patients on follow-up. CONCLUSION: IPL is an effective and safe alternative to otherwise difficult-to-treat acne-induced PIE.
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spelling pubmed-59568612018-05-31 Intense Pulsed Light Therapy for Acne-induced Post-inflammatory Erythema Mathew, Minu L. Karthik, R. Mallikarjun, M. Bhute, Soumya Varghese, Aiswarya Indian Dermatol Online J Original Article BACKGROUND: Intense pulsed light (IPL) is a comparatively new system of practice in treating acne-induced post inflammatory erythema (PIE) which is a difficult condition to treat, and variations exist in the results from published studies with insufficient or limited scientific evidence of IPL on Indian skin. AIM: To study the efficacy of IPL in the treatment of acne-induced PIE and to document adverse effects of the procedure. SETTINGS AND DESIGN: A hospital-based retrospective observational study on 33 patients with acne-induced PIE who completed treatment with IPL during the time period of July 2015 to June 2017. PATIENTS AND METHODS: All 33 patients were treated with vascular mode of IPL using 560-nm filter every 3 weeks for three to six sessions. Grading of PIE was done by Clinician Erythema Severity Score, and the objective parameters were assessed statistically for improvement using photographs. Adverse effects were noted and followed up. STATISTICAL ANALYSIS: Wilcoxon sign rank test and Pearson's correlation. RESULTS: There was statistically significant reduction in mean erythema score from 2.57 ± 0.66 to 1.21 ± 0.48 following IPL (Z = −5.295, P < 0.001—Wilcoxon sign rank test). Excellent improvement was noted in 11 (33.33%), good in 15 (45.45%), fair in 4 (12.12%), and poor in 3 (9.09%), and the results were consistent on follow-up. Adverse effects included erythema, hyperpigmentation, and hypopigmentation which were all transient and resolved completely in all patients on follow-up. CONCLUSION: IPL is an effective and safe alternative to otherwise difficult-to-treat acne-induced PIE. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5956861/ /pubmed/29854634 http://dx.doi.org/10.4103/idoj.IDOJ_306_17 Text en Copyright: © 2018 Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Mathew, Minu L.
Karthik, R.
Mallikarjun, M.
Bhute, Soumya
Varghese, Aiswarya
Intense Pulsed Light Therapy for Acne-induced Post-inflammatory Erythema
title Intense Pulsed Light Therapy for Acne-induced Post-inflammatory Erythema
title_full Intense Pulsed Light Therapy for Acne-induced Post-inflammatory Erythema
title_fullStr Intense Pulsed Light Therapy for Acne-induced Post-inflammatory Erythema
title_full_unstemmed Intense Pulsed Light Therapy for Acne-induced Post-inflammatory Erythema
title_short Intense Pulsed Light Therapy for Acne-induced Post-inflammatory Erythema
title_sort intense pulsed light therapy for acne-induced post-inflammatory erythema
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956861/
https://www.ncbi.nlm.nih.gov/pubmed/29854634
http://dx.doi.org/10.4103/idoj.IDOJ_306_17
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