Development and characterization of a nanoemulsion containing propranolol for topical delivery

BACKGROUND: Propranolol (PPN) is a therapeutic option for the treatment of infantile hemangiomas. This study aimed at the development of nanoemulsion (NE) containing 1% PPN, characterization of the system, and safety studies based on ex vivo permeation, cytotoxicity, and biodistribution in vivo. MET...

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Detalles Bibliográficos
Autores principales: Zanela da Silva Marques, Tatiana, Santos-Oliveira, Ralph, Betzler de Oliveira de Siqueira, Luciana, Cardoso, Verônica da Silva, de Freitas, Zaida Maria Faria, Barros, Rita de Cássia da Silva Ascenção, Villa, Ana Lúcia Vazquez, Monteiro, Mariana Sato de Souza de Bustamante, dos Santos, Elisabete Pereira, Ricci-Junior, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957063/
https://www.ncbi.nlm.nih.gov/pubmed/29785109
http://dx.doi.org/10.2147/IJN.S164404

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