Treatment Decisions of World Health Organization Grade II and III Ependymomas in Molecular Era

Surgery and radiotherapy are mainstays of treatment for ependymomas (EPNs). Recent molecular subgrouping could be superior to histopathological grading for predicting the prognosis of patients with EPNs. Gross total resection is an effective treatment approach regardless of its locations or patholog...

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Detalles Bibliográficos
Autores principales: Jung, Tae-Young, Jung, Shin, Kook, Hoon, Baek, Hee-Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurosurgical Society 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957310/
https://www.ncbi.nlm.nih.gov/pubmed/29742878
http://dx.doi.org/10.3340/jkns.2018.0003
Descripción
Sumario:Surgery and radiotherapy are mainstays of treatment for ependymomas (EPNs). Recent molecular subgrouping could be superior to histopathological grading for predicting the prognosis of patients with EPNs. Gross total resection is an effective treatment approach regardless of its locations or pathologic grades. Adjuvant therapeutic strategies could be decided based on molecular subgrouping with risk-stratification. Information of histologic-molecular biology is now providing clues to therapeutic insights.

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