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Diffuse Intrinsic Pontine Glioma : Clinical Features, Molecular Genetics, and Novel Targeted Therapeutics

Diffuse intrinsic pontine glioma (DIPG) is a deadly paediatric brain cancer. Transient response to radiation, ineffective chemotherapeutic agents and aggressive biology result in rapid progression of symptoms and a dismal prognosis. Increased availability of tumour tissue has enabled the identificat...

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Detalles Bibliográficos
Autores principales: Mathew, Ryan K., Rutka, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurosurgical Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957322/
https://www.ncbi.nlm.nih.gov/pubmed/29742880
http://dx.doi.org/10.3340/jkns.2018.0008