Ability of γδ T cells to modulate the Foxp3 T cell response is dependent on adenosine

Whether γδ T cells inhibit or enhance the Foxp3 T cell response depends upon their activation status. The critical enhancing effector in the supernatant is adenosine. Activated γδ T cells express adenosine receptors at high levels, which enables them to deprive Foxp3(+) T cells of adenosine, and to...

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Detalles Bibliográficos
Autores principales: Liang, Dongchun, Woo, Jeong-Im, Shao, Hui, Born, Willi K., O'Brien, Rebecca L., Kaplan, Henry J., Sun, Deming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957379/
https://www.ncbi.nlm.nih.gov/pubmed/29771938
http://dx.doi.org/10.1371/journal.pone.0197189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957379/
https://www.ncbi.nlm.nih.gov/pubmed/29771938
http://dx.doi.org/10.1371/journal.pone.0197189

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