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Ability of γδ T cells to modulate the Foxp3 T cell response is dependent on adenosine
Whether γδ T cells inhibit or enhance the Foxp3 T cell response depends upon their activation status. The critical enhancing effector in the supernatant is adenosine. Activated γδ T cells express adenosine receptors at high levels, which enables them to deprive Foxp3(+) T cells of adenosine, and to...
Autores principales: | Liang, Dongchun, Woo, Jeong-Im, Shao, Hui, Born, Willi K., O'Brien, Rebecca L., Kaplan, Henry J., Sun, Deming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957379/ https://www.ncbi.nlm.nih.gov/pubmed/29771938 http://dx.doi.org/10.1371/journal.pone.0197189 |
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