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Regulation of vitamin D metabolizing enzymes in murine renal and extrarenal tissues by dietary phosphate, FGF23, and 1,25(OH)(2)D(3)
BACKGROUND: The 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) together with parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23) regulates calcium (Ca(2+)) and phosphate (Pi) homeostasis, 1,25(OH)(2)D(3) synthesis is mediated by hydroxylases of the cytochrome P450 (Cyp) family. Vitamin D...
Autores principales: | Kägi, Larissa, Bettoni, Carla, Pastor-Arroyo, Eva M., Schnitzbauer, Udo, Hernando, Nati, Wagner, Carsten A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957386/ https://www.ncbi.nlm.nih.gov/pubmed/29771914 http://dx.doi.org/10.1371/journal.pone.0195427 |
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