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Cooperation of BMP and IHH signaling in interdigital cell fate determination

The elaborate anatomy of hands and feet is shaped by coordinated formation of digits and regression of the interdigital mesenchyme (IM). A failure of this process causes persistence of interdigital webbing and consequently cutaneous syndactyly. Bone morphogenetic proteins (BMPs) are key inductive fa...

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Detalles Bibliográficos
Autores principales: Murgai, Arunima, Altmeyer, Sara, Wiegand, Stephanie, Tylzanowski, Przemko, Stricker, Sigmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957397/
https://www.ncbi.nlm.nih.gov/pubmed/29771958
http://dx.doi.org/10.1371/journal.pone.0197535