Role of endothelin-1 in lung disease

Endothelin-1 (ET-1) is a 21 amino acid peptide with diverse biological activity that has been implicated in numerous diseases. ET-1 is a potent mitogen regulator of smooth muscle tone, and inflammatory mediator that may play a key role in diseases of the airways, pulmonary circulation, and inflammat...

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Detalles Bibliográficos
Autores principales: Fagan, Karen A, McMurtry, Ivan F, Rodman, David M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59574/
https://www.ncbi.nlm.nih.gov/pubmed/11686871
http://dx.doi.org/10.1186/rr44
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author Fagan, Karen A
McMurtry, Ivan F
Rodman, David M
author_facet Fagan, Karen A
McMurtry, Ivan F
Rodman, David M
author_sort Fagan, Karen A
collection PubMed
description Endothelin-1 (ET-1) is a 21 amino acid peptide with diverse biological activity that has been implicated in numerous diseases. ET-1 is a potent mitogen regulator of smooth muscle tone, and inflammatory mediator that may play a key role in diseases of the airways, pulmonary circulation, and inflammatory lung diseases, both acute and chronic. This review will focus on the biology of ET-1 and its role in lung disease.
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spelling pubmed-595742001-11-06 Role of endothelin-1 in lung disease Fagan, Karen A McMurtry, Ivan F Rodman, David M Respir Res Review Endothelin-1 (ET-1) is a 21 amino acid peptide with diverse biological activity that has been implicated in numerous diseases. ET-1 is a potent mitogen regulator of smooth muscle tone, and inflammatory mediator that may play a key role in diseases of the airways, pulmonary circulation, and inflammatory lung diseases, both acute and chronic. This review will focus on the biology of ET-1 and its role in lung disease. BioMed Central 2001 2001-02-22 /pmc/articles/PMC59574/ /pubmed/11686871 http://dx.doi.org/10.1186/rr44 Text en Copyright © 2001 BioMed Central Ltd
spellingShingle Review
Fagan, Karen A
McMurtry, Ivan F
Rodman, David M
Role of endothelin-1 in lung disease
title Role of endothelin-1 in lung disease
title_full Role of endothelin-1 in lung disease
title_fullStr Role of endothelin-1 in lung disease
title_full_unstemmed Role of endothelin-1 in lung disease
title_short Role of endothelin-1 in lung disease
title_sort role of endothelin-1 in lung disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59574/
https://www.ncbi.nlm.nih.gov/pubmed/11686871
http://dx.doi.org/10.1186/rr44
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AT mcmurtryivanf roleofendothelin1inlungdisease
AT rodmandavidm roleofendothelin1inlungdisease

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