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Maternal human telomerase reverse transcriptase variants are associated with preterm labor and preterm premature rupture of membranes

OBJECTIVE: Premature aging and short telomere lengths of fetal tissues are associated with spontaneous preterm labor (PTL) and preterm premature rupture of membranes (pPROM). Maintenance of telomere length is performed by the enzyme telomerase. Human telomerase reverse transcriptase (hTERT) is a sub...

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Detalles Bibliográficos
Autores principales: Marrs, Caroline, Chesmore, Kevin, Menon, Ramkumar, Williams, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957404/
https://www.ncbi.nlm.nih.gov/pubmed/29771920
http://dx.doi.org/10.1371/journal.pone.0195963