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Evaluation of commercial DNA and RNA extraction methods for high-throughput sequencing of FFPE samples
Nucleic acid material of adequate quality is crucial for successful high-throughput sequencing (HTS) analysis. DNA and RNA isolated from archival FFPE material are frequently degraded and not readily amplifiable due to chemical damage introduced during fixation. To identify optimal nucleic acid extr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957415/ https://www.ncbi.nlm.nih.gov/pubmed/29771965 http://dx.doi.org/10.1371/journal.pone.0197456 |