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Inactivation of bpsl1039-1040 ATP-binding cassette transporter reduces intracellular survival in macrophages, biofilm formation and virulence in the murine model of Burkholderia pseudomallei infection
Burkholderia pseudomallei, a gram-negative intracellular bacillus, is the causative agent of a tropical infectious disease called melioidosis. Bacterial ATP-binding cassette (ABC) transporters import and export a variety of molecules across bacterial cell membranes. At present, their significance in...
Autores principales: | Pinweha, Peechanika, Pumirat, Pornpan, Cuccui, Jon, Jitprasutwit, Niramol, Muangsombut, Veerachat, Srinon, Varintip, Boonyuen, Usa, Thiennimitr, Parameth, Vattanaviboon, Paiboon, Cia, Felipe, Willcocks, Sam, Bancroft, Gregory J., Wren, Brendan W., Korbsrisate, Sunee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957425/ https://www.ncbi.nlm.nih.gov/pubmed/29771915 http://dx.doi.org/10.1371/journal.pone.0196202 |
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