LncRNA Jpx induces Xist expression in mice using both trans and cis mechanisms

Mammalian X chromosome dosage compensation balances X-linked gene products between sexes and is coordinated by the long noncoding RNA (lncRNA) Xist. Multiple cis and trans-acting factors modulate Xist expression; however, the primary competence factor responsible for activating Xist remains a subjec...

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Detalles Bibliográficos
Autores principales: Carmona, Sarah, Lin, Benjamin, Chou, Tristan, Arroyo, Katti, Sun, Sha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957434/
https://www.ncbi.nlm.nih.gov/pubmed/29734339
http://dx.doi.org/10.1371/journal.pgen.1007378

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