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Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart
Fibroblasts are a dynamic cell type that achieve selective differentiated states to mediate acute wound healing and long-term tissue remodeling with scarring. With myocardial infarction injury, cardiomyocytes are replaced by secreted extracellular matrix proteins produced by proliferating and differ...
Autores principales: | Fu, Xing, Khalil, Hadi, Kanisicak, Onur, Boyer, Justin G., Vagnozzi, Ronald J., Maliken, Bryan D., Sargent, Michelle A., Prasad, Vikram, Valiente-Alandi, Iñigo, Blaxall, Burns C., Molkentin, Jeffery D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957472/ https://www.ncbi.nlm.nih.gov/pubmed/29664017 http://dx.doi.org/10.1172/JCI98215 |
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