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The lung as a route for systemic delivery of therapeutic proteins and peptides
The large surface area, good vascularization, immense capacity for solute exchange and ultra-thinness of the alveolar epithelium are unique features of the lung that can facilitate systemic delivery via pulmonary administration of peptides and proteins. Physical and biochemical barriers, lack of opt...
Autores principales: | Uchenna Agu, Remigius, Ikechukwu Ugwoke, Michael, Armand, Michoel, Kinget, Renaat, Verbeke, Norbert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59577/ https://www.ncbi.nlm.nih.gov/pubmed/11686885 http://dx.doi.org/10.1186/rr58 |
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