Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans

Genetically modified mice models suggest an important role for G-protein-coupled receptor kinase 5 (GRK5) in the pathophysiology of obesity and related disorders. We investigated whether single nucleotide polymorphisms (SNPs) in the gene encoding GRK5 affect cardiometabolic traits in humans. We geno...

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Detalles Bibliográficos
Autores principales: Lutz, Stefan Z., Falcenberg, Mathias, Machicao, Fausto, Peter, Andreas, Kächele, Martin, Randrianarisoa, Elko, Lehn-Stefan, Angela, Wagner, Robert, Machann, Jürgen, Schick, Fritz, Heni, Martin, Ullrich, Axel, Fritsche, Andreas, Stefan, Norbert, Häring, Hans-Ulrich, Staiger, Harald, Kantartzis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958094/
https://www.ncbi.nlm.nih.gov/pubmed/29773828
http://dx.doi.org/10.1038/s41598-018-26055-7

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