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Layer-by-layer siRNA/poly(L-lysine) Multilayers on Polydopamine-coated Surface for Efficient Cell Adhesion and Gene Silencing

For tissue engineering applications, small interfering RNA (siRNA) is an attractive agent for controlling cellular functions and differentiation. Although polyionic condensation of nucleic acids with polycations has been widely used for gene delivery, siRNA is not strongly associated with cationic c...

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Detalles Bibliográficos
Autores principales: Hong, Cheol Am, Son, Ho Yeon, Nam, Yoon Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958135/
https://www.ncbi.nlm.nih.gov/pubmed/29773839
http://dx.doi.org/10.1038/s41598-018-25655-7