Tetraspanin blockage reduces exosome-mediated HIV-1 entry

HIV-1 is one of the most studied retroviruses. The role of exosomes in HIV-1 entry and pathogenesis are beginning to be appreciated. Exosomes can incorporate host proteins that are also contained in viruses (e.g., tetraspanins).

Detalles Bibliográficos
Autores principales: Sims, Brian, Farrow, Anitra L., Williams, Sparkle D., Bansal, Anju, Krendelchtchikov, Alexandre, Matthews, Qiana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2018
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958159/
https://www.ncbi.nlm.nih.gov/pubmed/29429034
http://dx.doi.org/10.1007/s00705-018-3737-6
Descripción
Sumario:HIV-1 is one of the most studied retroviruses. The role of exosomes in HIV-1 entry and pathogenesis are beginning to be appreciated. Exosomes can incorporate host proteins that are also contained in viruses (e.g., tetraspanins).

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