Gemcabene, a First-in-Class Hypolipidemic Small Molecule in Clinical Development, Attenuates Osteoarthritis and Pain in Animal Models of Arthritis and Pain

Our clinical studies have demonstrated that gemcabene, a small molecule in late-stage clinical development, lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP). This observation was further confirmed in a cell-based study showing inhibition of cytokine-induced CRP production. Based...

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Detalles Bibliográficos
Autores principales: Srivastava, Rai A. K., Cornicelli, Joseph A., Markham, Bruce, Bisgaier, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958179/
https://www.ncbi.nlm.nih.gov/pubmed/29867478
http://dx.doi.org/10.3389/fphar.2018.00471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958179/
https://www.ncbi.nlm.nih.gov/pubmed/29867478
http://dx.doi.org/10.3389/fphar.2018.00471

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