Cargando…

Safety and Efficacy of Topical Chitogel- Deferiprone-Gallium Protoporphyrin in Sheep Model

Objectives: Increasing antimicrobial resistance has presented new challenges to the treatment of recalcitrant chronic rhinosinusitis fuelling a continuous search for novel antibiofilm agents. This study aimed to assess the safety and efficacy of Chitogel (Chitogel®, Wellington New Zealand) combined...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ooi, Mian L., Richter, Katharina, Drilling, Amanda J., Thomas, Nicky, Prestidge, Clive A., James, Craig, Moratti, Stephen, Vreugde, Sarah, Psaltis, Alkis J., Wormald, Peter-John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958210/ https://www.ncbi.nlm.nih.gov/pubmed/29867828 http://dx.doi.org/10.3389/fmicb.2018.00917

Ejemplares similares

Deferiprone and Gallium-Protoporphyrin Have the Capacity to Potentiate the Activity of Antibiotics in Staphylococcus aureus Small Colony Variants
por: Richter, Katharina, et al.
Publicado: (2017)

Prevention of adhesions post-abdominal surgery: Assessing the safety and efficacy of Chitogel with Deferiprone in a rat model
por: Vediappan, Rajan Sundaresan, et al.
Publicado: (2021)

Deferiprone has anti-inflammatory properties and reduces fibroblast migration in vitro
por: Ramezanpour, Mahnaz, et al.
Publicado: (2019)

Topical Colloidal Silver for the Treatment of Recalcitrant Chronic Rhinosinusitis
por: Ooi, Mian L., et al.
Publicado: (2018)

Gallium Protoporphyrin Liquid Crystalline Lipid Nanoparticles: A Third-Generation Photosensitizer against Pseudomonas aeruginosa Biofilms
por: Awad, Muhammed, et al.
Publicado: (2022)

Chitogel following endoscopic sinus surgery promotes a healthy microbiome and reduces postoperative infections
por: Megow, Anna, et al.
Publicado: (2022)

Long-Term Safety of Topical Bacteriophage Application to the Frontal Sinus Region
por: Drilling, Amanda J., et al.
Publicado: (2017)

Alloiococcus otitidis Forms Multispecies Biofilm with Haemophilus influenzae: Effects on Antibiotic Susceptibility and Growth in Adverse Conditions
por: Chan, Chun L., et al.
Publicado: (2017)

Reduced Innate Immune Response to a Staphylococcus aureus Small Colony Variant Compared to Its Wild-Type Parent Strain
por: Ou, Judy J. J., et al.
Publicado: (2016)

Chronic Rhinosinusitis with Polyps Is Characterized by Increased Mucosal and Blood Th17 Effector Cytokine Producing Cells
por: Miljkovic, Dijana, et al.
Publicado: (2017)

Distribution and Inhibition of Liposomes on Staphylococcus aureus and Pseudomonas aeruginosa Biofilm
por: Dong, Dong, et al.
Publicado: (2015)

Staphylococcus aureus from patients with chronic rhinosinusitis show minimal genetic association between polyp and non-polyp phenotypes
por: Bardy, Jake Jervis, et al.
Publicado: (2018)

Activity of Bacteriophages in Removing Biofilms of Pseudomonas aeruginosa Isolates from Chronic Rhinosinusitis Patients
por: Fong, Stephanie A., et al.
Publicado: (2017)

Primary human nasal epithelial cells: a source of poly (I:C) LMW-induced IL-6 production
por: Ramezanpour, Mahnaz, et al.
Publicado: (2018)

Sinonasal Microbiome Sampling: A Comparison of Techniques
por: Bassiouni, Ahmed, et al.
Publicado: (2015)

Antibiotics Affect ROS Production and Fibroblast Migration in an In-vitro Model of Sinonasal Wound Healing
por: Gouzos, Michael, et al.
Publicado: (2020)

Chronic Rhinosinusitis, S. aureus Biofilm and Secreted Products, Inflammatory Responses, and Disease Severity
por: Shaghayegh, Gohar, et al.
Publicado: (2022)

Pharokka: a fast scalable bacteriophage annotation tool
por: Bouras, George, et al.
Publicado: (2022)

Staphylococcal protein A modulates inflammation by inducing interferon signaling in human nasal epithelial cells
por: Hu, Hua, et al.
Publicado: (2022)

Gallium-Protoporphyrin IX Inhibits Pseudomonas aeruginosa Growth by Targeting Cytochromes
por: Hijazi, Sarah, et al.
Publicado: (2017)

Sub-Inhibitory Clindamycin and Azithromycin reduce S. aureus Exoprotein Induced Toxicity, Inflammation, Barrier Disruption and Invasion
por: Hu, Hua, et al.
Publicado: (2019)

Cytokine-Induced Modulation of SARS-CoV2 Receptor Expression in Primary Human Nasal Epithelial Cells
por: Ramezanpour, Mahnaz, et al.
Publicado: (2021)

Preclinical Development of a Bacteriophage Cocktail for Treating Multidrug Resistant Pseudomonas aeruginosa Infections
por: Camens, Sophie, et al.
Publicado: (2021)

APTC-EC-2A: A Lytic Phage Targeting Multidrug Resistant E. coli Planktonic Cells and Biofilms
por: Hon, Karen, et al.
Publicado: (2022)

APTC-C-SA01: A Novel Bacteriophage Cocktail Targeting Staphylococcus aureus and MRSA Biofilms
por: Liu, Sha, et al.
Publicado: (2022)

Colloidal silver against macrophage infections and biofilms of atypical mycobacteria
por: Feizi, Sholeh, et al.
Publicado: (2023)

Comparative Viral Sampling in the Sinonasal Passages; Different Viruses at Different Sites
por: Goggin, Rachel K., et al.
Publicado: (2018)

Corynebacterium accolens Has Antimicrobial Activity against Staphylococcus aureus and Methicillin-Resistant S. aureus Pathogens Isolated from the Sinonasal Niche of Chronic Rhinosinusitis Patients
por: Menberu, Martha Alemayehu, et al.
Publicado: (2021)

Prophages encoding human immune evasion cluster genes are enriched in Staphylococcus aureus isolated from chronic rhinosinusitis patients with nasal polyps
por: Nepal, Roshan, et al.
Publicado: (2021)

Liposome-Encapsulated ISMN: A Novel Nitric Oxide-Based Therapeutic Agent against Staphylococcus aureus Biofilms
por: Jardeleza, Camille, et al.
Publicado: (2014)

In vitro safety and anti‐bacterial efficacy assessment of acriflavine
por: Javadiyan, Shari, et al.
Publicado: (2022)

Activity of Gallium Meso- and Protoporphyrin IX against Biofilms of Multidrug-Resistant Acinetobacter baumannii Isolates
por: Chang, David, et al.
Publicado: (2016)

Pseudomonas aeruginosa Exoprotein-Induced Barrier Disruption Correlates With Elastase Activity and Marks Chronic Rhinosinusitis Severity
por: Li, Jian, et al.
Publicado: (2019)

A Novel Rat Model to Test Intra-Abdominal Anti-adhesive Therapy
por: Vediappan, Rajan Sundaresan, et al.
Publicado: (2020)

Characterization of human nasal organoids from chronic rhinosinusitis patients
por: Ramezanpour, Mahnaz, et al.
Publicado: (2022)

Der p 1 Disrupts the Epithelial Barrier and Induces IL-6 Production in Patients With House Dust Mite Allergic Rhinitis
por: Ogi, Kazuhiro, et al.
Publicado: (2021)

Dacryocystorhinostomy ostium: parameters to evaluate and DCR ostium scoring
por: Ali, Mohammad Javed, et al.
Publicado: (2014)

Salmonella Typhimurium and Pseudomonas aeruginosa Respond Differently to the Fe Chelator Deferiprone and to Some Novel Deferiprone Derivatives
por: Ammendola, Serena, et al.
Publicado: (2021)

Increased Serum IgG4 Associates with Asthma and Tissue Eosinophilia in Chronic Rhinosinusitis Patients
por: Ramezanpour, Mahnaz, et al.
Publicado: (2020)

Reddish Colour in Cooked Ham Is Developed by a Mixture of Protoporphyrins Including Zn-Protoporphyrin and Protoporphyrin IX
por: Giménez-Campillo, Claudia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nqko4hjb5po9v6aer5bj18d0sr