The current landscape of nucleic acid tests for filovirus detection

Nucleic acid testing (NAT) for pathogenic filoviruses plays a key role in surveillance and to control the spread of infection. As they share clinical features with other pathogens, the initial spread of these viruses can be misdiagnosed. Tests that can identify a pathogen in the initial stages of in...

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Autores principales: Clark, David J., Tyson, John, Sails, Andrew D., Krishna, Sanjeev, Staines, Henry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958242/
https://www.ncbi.nlm.nih.gov/pubmed/29625392
http://dx.doi.org/10.1016/j.jcv.2018.03.005
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author Clark, David J.
Tyson, John
Sails, Andrew D.
Krishna, Sanjeev
Staines, Henry M.
author_facet Clark, David J.
Tyson, John
Sails, Andrew D.
Krishna, Sanjeev
Staines, Henry M.
author_sort Clark, David J.
collection PubMed
description Nucleic acid testing (NAT) for pathogenic filoviruses plays a key role in surveillance and to control the spread of infection. As they share clinical features with other pathogens, the initial spread of these viruses can be misdiagnosed. Tests that can identify a pathogen in the initial stages of infection are essential to control outbreaks. Since the Ebola virus disease (EVD) outbreak in 2014–2016 several tests have been developed that are faster than previous tests and more suited for field use. Furthermore, the ability to test for a range of pathogens simultaneously has been expanded to improve clinical pathway management of febrile syndromes. This review provides an overview of these novel diagnostic tests.
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spelling pubmed-59582422018-06-01 The current landscape of nucleic acid tests for filovirus detection Clark, David J. Tyson, John Sails, Andrew D. Krishna, Sanjeev Staines, Henry M. J Clin Virol Article Nucleic acid testing (NAT) for pathogenic filoviruses plays a key role in surveillance and to control the spread of infection. As they share clinical features with other pathogens, the initial spread of these viruses can be misdiagnosed. Tests that can identify a pathogen in the initial stages of infection are essential to control outbreaks. Since the Ebola virus disease (EVD) outbreak in 2014–2016 several tests have been developed that are faster than previous tests and more suited for field use. Furthermore, the ability to test for a range of pathogens simultaneously has been expanded to improve clinical pathway management of febrile syndromes. This review provides an overview of these novel diagnostic tests. Elsevier Science 2018-06 /pmc/articles/PMC5958242/ /pubmed/29625392 http://dx.doi.org/10.1016/j.jcv.2018.03.005 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Clark, David J.
Tyson, John
Sails, Andrew D.
Krishna, Sanjeev
Staines, Henry M.
The current landscape of nucleic acid tests for filovirus detection
title The current landscape of nucleic acid tests for filovirus detection
title_full The current landscape of nucleic acid tests for filovirus detection
title_fullStr The current landscape of nucleic acid tests for filovirus detection
title_full_unstemmed The current landscape of nucleic acid tests for filovirus detection
title_short The current landscape of nucleic acid tests for filovirus detection
title_sort current landscape of nucleic acid tests for filovirus detection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958242/
https://www.ncbi.nlm.nih.gov/pubmed/29625392
http://dx.doi.org/10.1016/j.jcv.2018.03.005
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