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Oxyntomodulin analogue increases energy expenditure via the glucagon receptor

The gut hormone oxyntomodulin (OXM) causes weight loss by reducing appetite and increasing energy expenditure. Several analogues are being developed to treat obesity. Exactly how oxyntomodulin works, however, remains controversial. OXM can activate both glucagon and GLP-1 receptors but no specific r...

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Detalles Bibliográficos
Autores principales: Scott, R., Minnion, J., Tan, T., Bloom, S.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958244/
https://www.ncbi.nlm.nih.gov/pubmed/29680267
http://dx.doi.org/10.1016/j.peptides.2018.04.008

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