Cargando…

Phenylmethimazole abrogates diet-induced inflammation, glucose intolerance and NAFLD

Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of both metabolic and inflammatory diseases and has become the leading chronic liver disease worldwide. High-fat (HF) diets promote an increased uptake and storage of free fatty acids (FFAs) and triglycerides (TGs) in hepatocytes,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Patton, Ashley, Church, Tyler, Wilson, Caroline, Thuma, Jean, Goetz, Douglas J, Berryman, Darlene E, List, Edward O, Schwartz, Frank, McCall, Kelly D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958349/ https://www.ncbi.nlm.nih.gov/pubmed/29666152 http://dx.doi.org/10.1530/JOE-18-0078

Ejemplares similares

Phenylmethimazole Blocks dsRNA-Induced IRF3 Nuclear Translocation and Homodimerization
por: Courreges, Maria C., et al.
Publicado: (2012)

SUN-095 Attenuation of Inflammation by a Novel Small Molecule Prevents High Fat Diet-Induced Nonalcoholic Fatty Liver Disease
por: Patton, Ashley, et al.
Publicado: (2019)

TLR signaling inhibitor, phenylmethimazole, in combination with tamoxifen inhibits human breast cancer cell viability and migration
por: Schwartz, Anthony L., et al.
Publicado: (2016)

Phenylmethimazole Suppresses dsRNA-Induced Cytotoxicity and Inflammatory Cytokines in Murine Pancreatic Beta Cells and Blocks Viral Acceleration of Type 1 Diabetes in NOD Mice
por: McCall, Kelly D., et al.
Publicado: (2013)

Anti-Inflammatory and Therapeutic Effects of a Novel Small-Molecule Inhibitor of Inflammation in a Male C57BL/6J Mouse Model of Obesity-Induced NAFLD/MAFLD
por: McCall, Kelly D, et al.
Publicado: (2023)

Diet Is Critical for Prolonged Glycemic Control after Short-Term Insulin Treatment in High-Fat Diet-Induced Type 2 Diabetic Male Mice
por: Guo, Aili, et al.
Publicado: (2015)

Differences in characteristics of glucose intolerance between patients with NAFLD and chronic hepatitis C as determined by CGMS
por: Ochi, Tsunehiro, et al.
Publicado: (2017)

Growth Hormone’s Effect on Adipose Tissue: Quality versus Quantity
por: Berryman, Darlene E., et al.
Publicado: (2017)

Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance
por: Sabrautzki, Sibylle, et al.
Publicado: (2017)

Antiretroviral therapy potentiates high-fat diet induced obesity and glucose intolerance
por: Pepin, Mark E., et al.
Publicado: (2018)

Diet-induced weight loss is sufficient to reduce senescent cell number in white adipose tissue of weight-cycled mice
por: List, Edward O., et al.
Publicado: (2016)

Phenylmethimazole is a candidate drug for the treatment of severe forms of coronavirus disease 2019 (COVID-19) as well as other virus-induced “cytokines storm”
por: Giuliani, Cesidio, et al.
Publicado: (2021)

Repression of GH signaling: One extended life to live!
por: Berryman, Darlene E., et al.
Publicado: (2013)

Chasing Methuselah: adult inducible GHRKO mice
por: Kopchick, John J., et al.
Publicado: (2022)

Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH
por: Tan, Mingjun, et al.
Publicado: (2020)

Transgenic Mice Overexpressing Renin Exhibit Glucose Intolerance and Diet-Genotype Interactions
por: Fletcher, Sarah J., et al.
Publicado: (2013)

Targeting viperin improves diet-induced glucose intolerance but not adipose tissue inflammation
por: Qi, Zhengtang, et al.
Publicado: (2017)

Selective breeding of mice for different susceptibilities to high fat diet‐induced glucose intolerance: Development of two novel mouse lines, Selectively bred Diet‐induced Glucose intolerance‐Prone and ‐Resistant
por: Nagao, Mototsugu, et al.
Publicado: (2012)

SUN-094 Altering Cycle Duration Of A Yoyo-diet Has No Effect On Mortality In Weight Cycled Mice
por: Slyby, Julie, et al.
Publicado: (2019)

MON-480 Reduced Respiration Observed In Isolated Liver Mitochondria Of Long-lived GHR-/- Mice At Early Ages
por: Funk, Kevin, et al.
Publicado: (2019)

Quinoa (Chenopodium quinoa Willd.) supplemented cafeteria diet ameliorates glucose intolerance in rats
por: Ozcaliskan Ilkay, Hatice, et al.
Publicado: (2023)

Proinsulin is sensitive to reflect glucose intolerance
por: Nakamura, Akinobu, et al.
Publicado: (2019)

Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance
por: Huynh, Frank K., et al.
Publicado: (2010)

Differential Development of Glucose Intolerance and Pancreatic Islet Adaptation in Multiple Diet Induced Obesity Models
por: Omar, Bilal, et al.
Publicado: (2012)

Isoform-Specific Role of GSK-3 in High Fat Diet Induced Obesity and Glucose Intolerance
por: Gupte, Manisha, et al.
Publicado: (2022)

Ketogenic Diets Induced Glucose Intolerance and Lipid Accumulation in Mice with Alterations in Gut Microbiota and Metabolites
por: Li, Yue, et al.
Publicado: (2021)

Ablation of the gut microbiota alleviates high-methionine diet-induced hyperhomocysteinemia and glucose intolerance in mice
por: Li, Wenqiang, et al.
Publicado: (2023)

Sugar Diet in Intolerant Ulcer of the Stomach
Publicado: (1914)

Transcriptional profiling identifies strain-specific effects of caloric restriction and opposite responses in human and mouse white adipose tissue
por: Swindell, William R., et al.
Publicado: (2018)

Consequences of Both Coxsackievirus B4 and Type 1 Diabetes on Female Non-Obese Diabetic Mouse Kidneys
por: Walter, Debra L., et al.
Publicado: (2021)

Blueberries’ Impact on Insulin Resistance and Glucose Intolerance
por: Stull, April J.
Publicado: (2016)

METABOLIC SYNDROME, GLUCOSE INTOLERANCE, AND PHYSICAL RESILIENCE
por: Kalyani, Rita, et al.
Publicado: (2022)

Erythropoietin Inhibits Gluconeogenesis and Inflammation in the Liver and Improves Glucose Intolerance in High-Fat Diet-Fed Mice
por: Meng, Ran, et al.
Publicado: (2013)

αB-crystallin and HspB2 deficiency is protective from diet-induced glucose intolerance
por: Toft, Daniel J., et al.
Publicado: (2016)

A Maternal High-Fat Diet Induces DNA Methylation Changes That Contribute to Glucose Intolerance in Offspring
por: Zhang, Qian, et al.
Publicado: (2019)

Fortifying Butterfat with Soybean Oil Attenuates the Onset of Diet-Induced Non-Alcoholic Steatohepatitis and Glucose Intolerance
por: Sánchez, Victor, et al.
Publicado: (2021)

Sucralose consumption ameliorates high-fat diet-induced glucose intolerance and liver weight gain in mice
por: Pino-Seguel, Pamela, et al.
Publicado: (2022)

NPFFR2-deficient mice fed a high-fat diet develop strong intolerance to glucose
por: Karnošová, Alena, et al.
Publicado: (2023)

Gallic Acid Ameliorated Impaired Glucose and Lipid Homeostasis in High Fat Diet-Induced NAFLD Mice
por: Chao, Jung, et al.
Publicado: (2014)

Diet and Exercise Exert a Differential Effect on Glucose Metabolism Markers According to the Degree of NAFLD Severity
por: Bianco, Antonella, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_78jhn2dacbqfqgjrfphksmvqrv