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Contemporary Management of Benign and Malignant Parotid Tumors
To report the standard of care, interesting new findings and controversies about the treatment of parotid tumors. Relevant and actual studies were searched in PubMed and reviewed for diagnostics, treatment and outcome of both benign and malignant tumors. Prospective trials are lacking due to rarity...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958460/ https://www.ncbi.nlm.nih.gov/pubmed/29868604 http://dx.doi.org/10.3389/fsurg.2018.00039 |
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author | Thielker, Jovanna Grosheva, Maria Ihrler, Stephan Wittig, Andrea Guntinas-Lichius, Orlando |
author_facet | Thielker, Jovanna Grosheva, Maria Ihrler, Stephan Wittig, Andrea Guntinas-Lichius, Orlando |
author_sort | Thielker, Jovanna |
collection | PubMed |
description | To report the standard of care, interesting new findings and controversies about the treatment of parotid tumors. Relevant and actual studies were searched in PubMed and reviewed for diagnostics, treatment and outcome of both benign and malignant tumors. Prospective trials are lacking due to rarity of the disease and high variety of tumor subtypes. The establishment of reliable non-invasive diagnostics tools for the differentiation between benign and malignant tumors is desirable. Prospective studies clarifying the association between different surgical techniques for benign parotid tumors and morbidity are needed. The role of adjuvant or definitive radiotherapy in securing loco-regional control and improving survival in malignant disease is established. Prospective clinical trials addressing the role of chemotherapy/molecular targeted therapy for parotid cancer are needed. An international consensus on the classification of parotid surgery techniques would facilitate the comparison of different trials. Such efforts should lead into a clinical guideline. |
format | Online Article Text |
id | pubmed-5958460 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-59584602018-06-04 Contemporary Management of Benign and Malignant Parotid Tumors Thielker, Jovanna Grosheva, Maria Ihrler, Stephan Wittig, Andrea Guntinas-Lichius, Orlando Front Surg Surgery To report the standard of care, interesting new findings and controversies about the treatment of parotid tumors. Relevant and actual studies were searched in PubMed and reviewed for diagnostics, treatment and outcome of both benign and malignant tumors. Prospective trials are lacking due to rarity of the disease and high variety of tumor subtypes. The establishment of reliable non-invasive diagnostics tools for the differentiation between benign and malignant tumors is desirable. Prospective studies clarifying the association between different surgical techniques for benign parotid tumors and morbidity are needed. The role of adjuvant or definitive radiotherapy in securing loco-regional control and improving survival in malignant disease is established. Prospective clinical trials addressing the role of chemotherapy/molecular targeted therapy for parotid cancer are needed. An international consensus on the classification of parotid surgery techniques would facilitate the comparison of different trials. Such efforts should lead into a clinical guideline. Frontiers Media S.A. 2018-05-11 /pmc/articles/PMC5958460/ /pubmed/29868604 http://dx.doi.org/10.3389/fsurg.2018.00039 Text en Copyright © 2018 Thielker, Grosheva, Ihrler, Wittig and Guntinas-Lichius http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Surgery Thielker, Jovanna Grosheva, Maria Ihrler, Stephan Wittig, Andrea Guntinas-Lichius, Orlando Contemporary Management of Benign and Malignant Parotid Tumors |
title | Contemporary Management of Benign and Malignant Parotid Tumors |
title_full | Contemporary Management of Benign and Malignant Parotid Tumors |
title_fullStr | Contemporary Management of Benign and Malignant Parotid Tumors |
title_full_unstemmed | Contemporary Management of Benign and Malignant Parotid Tumors |
title_short | Contemporary Management of Benign and Malignant Parotid Tumors |
title_sort | contemporary management of benign and malignant parotid tumors |
topic | Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958460/ https://www.ncbi.nlm.nih.gov/pubmed/29868604 http://dx.doi.org/10.3389/fsurg.2018.00039 |
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