Cargando…

Contemporary Management of Benign and Malignant Parotid Tumors

To report the standard of care, interesting new findings and controversies about the treatment of parotid tumors. Relevant and actual studies were searched in PubMed and reviewed for diagnostics, treatment and outcome of both benign and malignant tumors. Prospective trials are lacking due to rarity...

Descripción completa

Detalles Bibliográficos
Autores principales: Thielker, Jovanna, Grosheva, Maria, Ihrler, Stephan, Wittig, Andrea, Guntinas-Lichius, Orlando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958460/
https://www.ncbi.nlm.nih.gov/pubmed/29868604
http://dx.doi.org/10.3389/fsurg.2018.00039
_version_ 1783324244062502912
author Thielker, Jovanna
Grosheva, Maria
Ihrler, Stephan
Wittig, Andrea
Guntinas-Lichius, Orlando
author_facet Thielker, Jovanna
Grosheva, Maria
Ihrler, Stephan
Wittig, Andrea
Guntinas-Lichius, Orlando
author_sort Thielker, Jovanna
collection PubMed
description To report the standard of care, interesting new findings and controversies about the treatment of parotid tumors. Relevant and actual studies were searched in PubMed and reviewed for diagnostics, treatment and outcome of both benign and malignant tumors. Prospective trials are lacking due to rarity of the disease and high variety of tumor subtypes. The establishment of reliable non-invasive diagnostics tools for the differentiation between benign and malignant tumors is desirable. Prospective studies clarifying the association between different surgical techniques for benign parotid tumors and morbidity are needed. The role of adjuvant or definitive radiotherapy in securing loco-regional control and improving survival in malignant disease is established. Prospective clinical trials addressing the role of chemotherapy/molecular targeted therapy for parotid cancer are needed. An international consensus on the classification of parotid surgery techniques would facilitate the comparison of different trials. Such efforts should lead into a clinical guideline.
format Online
Article
Text
id pubmed-5958460
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-59584602018-06-04 Contemporary Management of Benign and Malignant Parotid Tumors Thielker, Jovanna Grosheva, Maria Ihrler, Stephan Wittig, Andrea Guntinas-Lichius, Orlando Front Surg Surgery To report the standard of care, interesting new findings and controversies about the treatment of parotid tumors. Relevant and actual studies were searched in PubMed and reviewed for diagnostics, treatment and outcome of both benign and malignant tumors. Prospective trials are lacking due to rarity of the disease and high variety of tumor subtypes. The establishment of reliable non-invasive diagnostics tools for the differentiation between benign and malignant tumors is desirable. Prospective studies clarifying the association between different surgical techniques for benign parotid tumors and morbidity are needed. The role of adjuvant or definitive radiotherapy in securing loco-regional control and improving survival in malignant disease is established. Prospective clinical trials addressing the role of chemotherapy/molecular targeted therapy for parotid cancer are needed. An international consensus on the classification of parotid surgery techniques would facilitate the comparison of different trials. Such efforts should lead into a clinical guideline. Frontiers Media S.A. 2018-05-11 /pmc/articles/PMC5958460/ /pubmed/29868604 http://dx.doi.org/10.3389/fsurg.2018.00039 Text en Copyright © 2018 Thielker, Grosheva, Ihrler, Wittig and Guntinas-Lichius http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Thielker, Jovanna
Grosheva, Maria
Ihrler, Stephan
Wittig, Andrea
Guntinas-Lichius, Orlando
Contemporary Management of Benign and Malignant Parotid Tumors
title Contemporary Management of Benign and Malignant Parotid Tumors
title_full Contemporary Management of Benign and Malignant Parotid Tumors
title_fullStr Contemporary Management of Benign and Malignant Parotid Tumors
title_full_unstemmed Contemporary Management of Benign and Malignant Parotid Tumors
title_short Contemporary Management of Benign and Malignant Parotid Tumors
title_sort contemporary management of benign and malignant parotid tumors
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958460/
https://www.ncbi.nlm.nih.gov/pubmed/29868604
http://dx.doi.org/10.3389/fsurg.2018.00039
work_keys_str_mv AT thielkerjovanna contemporarymanagementofbenignandmalignantparotidtumors
AT groshevamaria contemporarymanagementofbenignandmalignantparotidtumors
AT ihrlerstephan contemporarymanagementofbenignandmalignantparotidtumors
AT wittigandrea contemporarymanagementofbenignandmalignantparotidtumors
AT guntinaslichiusorlando contemporarymanagementofbenignandmalignantparotidtumors