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Oct4 suppresses IR-induced premature senescence in breast cancer cells through STAT3- and NF-κB-mediated IL-24 production

Breast cancer stem cells (BCSCs) are a small subpopulation of breast cancer cells that have been proposed to be a primary cause of failure of therapies, including ionizing radiation (IR). Their embryonic stem-like signature is associated with poor clinical outcome. In the present study, the function...

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Detalles Bibliográficos
Autores principales: Kim, Jeong-Yub, Kim, Jeong-Chul, Lee, Ji-Yun, Park, Myung-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958730/
https://www.ncbi.nlm.nih.gov/pubmed/29749438
http://dx.doi.org/10.3892/ijo.2018.4391

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