Cargando…

Oct4 suppresses IR-induced premature senescence in breast cancer cells through STAT3- and NF-κB-mediated IL-24 production

Breast cancer stem cells (BCSCs) are a small subpopulation of breast cancer cells that have been proposed to be a primary cause of failure of therapies, including ionizing radiation (IR). Their embryonic stem-like signature is associated with poor clinical outcome. In the present study, the function...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Jeong-Yub, Kim, Jeong-Chul, Lee, Ji-Yun, Park, Myung-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958730/ https://www.ncbi.nlm.nih.gov/pubmed/29749438 http://dx.doi.org/10.3892/ijo.2018.4391

Ejemplares similares

IL-6-STAT3 signaling and premature senescence
por: Kojima, Hirotada, et al.
Publicado: (2013)

Dietary Curcumin Attenuates Hepatic Cellular Senescence by Suppressing the MAPK/NF-κB Signaling Pathway in Aged Mice
por: Lee, Da-Yeon, et al.
Publicado: (2023)

NF-κB in premature aging
por: Osorio, Fernando G., et al.
Publicado: (2012)

Inflammation, cytokines, the IL-17/IL-6/STAT3/NF-κB axis, and tumorigenesis
por: Chen, Xiao-Wu, et al.
Publicado: (2015)

Adiponectin Suppresses UVB-Induced Premature Senescence and hBD2 Overexpression in Human Keratinocytes
por: Kim, MinJeong, et al.
Publicado: (2016)

Correction: Adiponectin Suppresses UVB-Induced Premature Senescence and hBD2 Overexpression in Human Keratinocytes
por: Kim, MinJeong, et al.
Publicado: (2016)

IL-32γ inhibits cancer cell growth through inactivation of NF-κB and STAT3 signals
por: Oh, J H, et al.
Publicado: (2011)

Docoxahexaenoic Acid Induces Apoptosis of Pancreatic Cancer Cells by Suppressing Activation of STAT3 and NF-κB
por: Park, Mirae, et al.
Publicado: (2018)

STAT3 and NF-κB are Simultaneously Suppressed in Dendritic Cells in Lung Cancer
por: Li, Rui, et al.
Publicado: (2017)

Antitumor activity of IL-32β through the activation of lymphocytes, and the inactivation of NF-κB and STAT3 signals
por: Yun, H-M, et al.
Publicado: (2013)

α-Lipoic Acid Inhibits Expression of IL-8 by Suppressing Activation of MAPK, Jak/Stat, and NF-κB in H. pylori-Infected Gastric Epithelial AGS Cells
por: Choi, Ji Hyun, et al.
Publicado: (2016)

NF-κB-Induced IL-6 Ensures STAT3 Activation and Tumor Aggressiveness in Glioblastoma
por: McFarland, Braden C., et al.
Publicado: (2013)

IRF9 and unphosphorylated STAT2 cooperate with NF-κB to drive IL6 expression
por: Nan, Jing, et al.
Publicado: (2018)

Regulation of Cr(VI)-Induced Premature Senescence in L02 Hepatocytes by ROS-Ca(2+)-NF-κB Signaling
por: Zhang, Yujing, et al.
Publicado: (2022)

Lipocalin 2 potentially contributes to tumorigenesis from colitis via IL-6/STAT3/NF-κB signaling pathway
por: Kim, Se Lim, et al.
Publicado: (2022)

NF-κB in Cellular Senescence and Cancer Treatment
por: Jing, Hua, et al.
Publicado: (2014)

Apigenin inhibits colonic inflammation and tumorigenesis by suppressing STAT3-NF-κB signaling
por: Ai, Xiao-Yu, et al.
Publicado: (2017)

A New Paradigm to Mitigate Osteosarcoma by Regulation of MicroRNAs and Suppression of the NF-κB Signaling Cascade
por: Mongre, Raj Kumar, et al.
Publicado: (2014)

Tolfenamic Acid Suppresses Inflammatory Stimuli-Mediated Activation of NF-κB Signaling
por: Shao, Hong Jun, et al.
Publicado: (2015)

Gomisin M2 Ameliorates Atopic Dermatitis-like Skin Lesions via Inhibition of STAT1 and NF-κB Activation in 2,4-Dinitrochlorobenzene/Dermatophagoides farinae Extract-Induced BALB/c Mice
por: Kang, Jinjoo, et al.
Publicado: (2021)

Methylsulfonylmethane Inhibits RANKL-Induced Osteoclastogenesis in BMMs by Suppressing NF-κB and STAT3 Activities
por: Joung, Youn Hee, et al.
Publicado: (2016)

Concurrent Treatment with Taxifolin and Cilostazol on the Lowering of β-Amyloid Accumulation and Neurotoxicity via the Suppression of P-JAK2/P-STAT3/NF-κB/BACE1 Signaling Pathways
por: Park, So Youn, et al.
Publicado: (2016)

Senescence and NFκB: A trojan horse in tumors?
por: Crescenzi, Elvira, et al.
Publicado: (2012)

Atorvastatin inhibits osteoclast differentiation by suppressing NF-κB and MAPK signaling during IL-1β-induced osteoclastogenesis
por: Lee, Won-Seok, et al.
Publicado: (2018)

IL-4 and IL-13 Promote Proliferation of Mammary Epithelial Cells through STAT6 and IRS-1
por: Wu, Wan-Ju, et al.
Publicado: (2021)

Down-Regulation of NF-κB Target Genes by the AP-1 and STAT Complex during the Innate Immune Response in Drosophila
por: Kim, Lark Kyun, et al.
Publicado: (2007)

Overexpression of Sirtuin 6 suppresses cellular senescence and NF-κB mediated inflammatory responses in osteoarthritis development
por: Wu, Yaosen, et al.
Publicado: (2015)

Inhibition of skin carcinogenesis by suppression of NF-κB dependent ITGAV and TIMP-1 expression in IL-32γ overexpressed condition
por: Lee, Yong Sun, et al.
Publicado: (2018)

Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts
por: Kang, Hyun Tae, et al.
Publicado: (2011)

Interleukin (IL)-25 suppresses IL-22-induced osteoclastogenesis in rheumatoid arthritis via STAT3 and p38 MAPK/IκBα pathway
por: Min, Hong Ki, et al.
Publicado: (2020)

Overexpression of a Minimal Domain of Calpastatin Suppresses IL-6 Production and Th17 Development via Reduced NF-κB and Increased STAT5 Signals
por: Iguchi-Hashimoto, Mikiko, et al.
Publicado: (2011)

CUEDC2 suppresses glioma tumorigenicity by inhibiting the activation of STAT3 and NF-κB signaling pathway
por: Li, Feng, et al.
Publicado: (2017)

Adiponectin Suppresses Metastasis of Nasopharyngeal Carcinoma through Blocking the Activation of NF-κB and STAT3 Signaling
por: Zhang, Zongmeng, et al.
Publicado: (2022)

Maslinic Acid Ameliorates Inflammation via the Downregulation of NF-κB and STAT-1
por: Lee, Wonhwa, et al.
Publicado: (2020)

The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNA-Induced Silencing of NF-κB–Inducing Kinase
por: Jang, Hanbit, et al.
Publicado: (2020)

Oxygen-Sensing Nox4 Generates Genotoxic ROS to Induce Premature Senescence of Nucleus Pulposus Cells through MAPK and NF-κB Pathways
por: Feng, Chencheng, et al.
Publicado: (2017)

17beta-estradiol Attenuates TNF-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway
por: Li, Pei, et al.
Publicado: (2017)

Jak1/Stat3 Is an Upstream Signaling of NF-κB Activation in Helicobacter pylori-Induced IL-8 Production in Gastric Epithelial AGS Cells
por: Cha, Boram, et al.
Publicado: (2015)

Anthocyanins Downregulate Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglial Cells by Suppressing the NF-κB and Akt/MAPKs Signaling Pathways
por: Jeong, Jin-Woo, et al.
Publicado: (2013)

STAT3/NF-κB decoy oligodeoxynucleotides inhibit atherosclerosis through regulation of the STAT/NF-κB signaling pathway in a mouse model of atherosclerosis
por: An, Hyun-Jin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q5n88s7a950prqcmhl24p10nsa