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Silibinin induces G1 arrest, apoptosis and JNK/SAPK upregulation in SW1990 human pancreatic cancer cells

The aim of the present study was to investigate the inhibitory effect of silibinin on SW1990 pancreatic cancer cells. An MTT assay following silibinin treatment demonstrated an inhibitory effect on AsPC-1 and SW1990 cells in a dose- and time-dependent manner. Propidium iodide staining analysis ident...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaokai, Liu, Jiming, Zhang, Peng, Dai, Liting, Wu, Zhihui, Wang, Li, Cao, Mingrong, Jiang, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958732/
https://www.ncbi.nlm.nih.gov/pubmed/29805688
http://dx.doi.org/10.3892/ol.2018.8541