Cargando…

Rapeseed protein-derived antioxidant peptide RAP alleviates renal fibrosis through MAPK/NF-κB signaling pathways in diabetic nephropathy

INTRODUCTION: Kidney fibrosis is the main pathologic change in diabetic nephropathy (DN), which is the major cause of end-stage renal disease. Current therapeutic strategies slow down but cannot reverse the progression of renal dysfunction in DN. Plant-derived bioactive peptides in foodstuffs are wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Mingyan, Yan, Zhibin, Bu, Lili, An, Chunmei, Wang, Dan, Liu, Xin, Zhang, Jianfeng, Yang, Wenle, Deng, Bochuan, Xie, Junqiu, Zhang, Bangzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958891/ https://www.ncbi.nlm.nih.gov/pubmed/29795979 http://dx.doi.org/10.2147/DDDT.S162288

Ejemplares similares

A novel and low-toxic peptide DR3penA alleviates pulmonary fibrosis by regulating the MAPK/miR-23b-5p/AQP5 signaling axis
por: Wang, Dan, et al.
Publicado: (2023)

The antimicrobial peptide YD attenuates inflammation via miR-155 targeting CASP12 during liver fibrosis
por: Yan, Zhibin, et al.
Publicado: (2021)

Kirenol alleviates diabetic nephropathy via regulating TGF-β/Smads and the NF-κB signal pathway
por: Li, Jialin, et al.
Publicado: (2022)

SOCS2 overexpression alleviates diabetic nephropathy in rats by inhibiting the TLR4/NF-κB pathway
por: Yang, Suxia, et al.
Publicado: (2017)

Genistein improves mitochondrial function and inflammatory in rats with diabetic nephropathy via inhibiting MAPK/NF-κB pathway
por: Li, Ying, et al.
Publicado: (2022)

Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways
por: Li, Baixing, et al.
Publicado: (2022)

Potent Antimicrobial and Antibiofilm Activities of Feleucin-K3 Analogs Modified by α-(4-Pentenyl)-Ala against Multidrug-Resistant Bacteria
por: Guo, Xiaomin, et al.
Publicado: (2021)

Tamarixinin A Alleviates Joint Destruction of Rheumatoid Arthritis by Blockade of MAPK and NF-κB Activation
por: Zhuang, Yuanyuan, et al.
Publicado: (2017)

(-)-α-Bisabolol Alleviates Atopic Dermatitis by Inhibiting MAPK and NF-κB Signaling in Mast Cell
por: Li, Guangxia, et al.
Publicado: (2022)

Harmine Alleviated Sepsis-Induced Cardiac Dysfunction by Modulating Macrophage Polarization via the STAT/MAPK/NF-κB Pathway
por: Ruan, Weibin, et al.
Publicado: (2022)

Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-κB and MAPK pathways
por: Chen, Yan, et al.
Publicado: (2018)

Breviscapine alleviates podocyte injury by inhibiting NF-κB/NLRP3-mediated pyroptosis in diabetic nephropathy
por: Sun, Linlin, et al.
Publicado: (2023)

Rap1 Ameliorates Renal Tubular Injury in Diabetic Nephropathy
por: Xiao, Li, et al.
Publicado: (2014)

SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axis
por: Liu, Fei, et al.
Publicado: (2018)

Ulinastatin alleviates early brain injury after intracerebral hemorrhage by inhibiting necroptosis and neuroinflammation via MAPK/NF-κB signaling pathway
por: Wang, Li, et al.
Publicado: (2022)

Rosmanol and Carnosol Synergistically Alleviate Rheumatoid Arthritis through Inhibiting TLR4/NF-κB/MAPK Pathway
por: Li, Lianchun, et al.
Publicado: (2021)

Poricoic Acid A Inhibits the NF-κB/MAPK Pathway to Alleviate Renal Fibrosis in Rats with Cardiorenal Syndrome
por: Chen, Wenzhong, et al.
Publicado: (2022)

Isoimperatorin alleviates lipopolysaccharide-induced periodontitis by downregulating ERK1/2 and NF-κB pathways
por: Fan, Lili, et al.
Publicado: (2023)

Huaiqihuang (HQH) granule alleviates cyclophosphamide-induced nephrotoxicity via suppressing the MAPK/NF-κB pathway and NLRP3 inflammasome activation
por: Zhang, Yueming, et al.
Publicado: (2021)

Alkaloids from Aconitum carmichaelii Alleviates DSS-Induced Ulcerative Colitis in Mice via MAPK/NF-κB/STAT3 Signaling Inhibition
por: Huang, Chuanqi, et al.
Publicado: (2022)

Hirudin Protects Against Kidney Damage in Streptozotocin-Induced Diabetic Nephropathy Rats by Inhibiting Inflammation via P38 MAPK/NF-κB Pathway
por: Han, Jiarui, et al.
Publicado: (2020)

4-Acetylantroquinonol B inhibits lipopolysaccharide-induced cytokine release and alleviates sepsis through of MAPK and NFκB suppression
por: Chang, Chien-Hsin, et al.
Publicado: (2018)

Downregulation of cathepsin C alleviates endothelial cell dysfunction by suppressing p38 MAPK/NF-κB pathway in preeclampsia
por: Lu, Fan, et al.
Publicado: (2022)

Osthole Alleviates D-Galactose-Induced Liver Injury In Vivo via the TLR4/MAPK/NF-κB Pathways
por: Ma, Zhe, et al.
Publicado: (2023)

The Extracts of Dendrobium Alleviate Dry Eye Disease in Rat Model by Regulating Aquaporin Expression and MAPKs/NF-κB Signalling
por: Ling, Jiawei, et al.
Publicado: (2022)

Combination of Niclosamide and Pirfenidone Alleviates Pulmonary Fibrosis by Inhibiting Oxidative Stress and MAPK/Nf-κB and STATs Regulated Genes
por: Wanas, Hanaa, et al.
Publicado: (2023)

Retracted: Poricoic Acid A Inhibits the NF-κB/MAPK Pathway to Alleviate Renal Fibrosis in Rats with Cardiorenal Syndrome
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Trichosanthes kirilowii lectin alleviates diabetic nephropathy by inhibiting the LOX1/NF-κB/caspase-9 signaling pathway
por: Lu, Jiandong, et al.
Publicado: (2018)

Ligustilide alleviates podocyte injury via suppressing the SIRT1/NF-κB signaling pathways in rats with diabetic nephropathy
por: Xu, Feng, et al.
Publicado: (2020)

Quzhou Fructus Aurantii Extract suppresses inflammation via regulation of MAPK, NF-κB, and AMPK signaling pathway
por: Li, Lili, et al.
Publicado: (2020)

Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway
por: Guo, Yujie, et al.
Publicado: (2023)

Eugenol alleviates transmissible gastroenteritis virus-induced intestinal epithelial injury by regulating NF-κB signaling pathway
por: Wang, Kang, et al.
Publicado: (2022)

Silicon Alleviates the Disease Severity of Sclerotinia Stem Rot in Rapeseed
por: Feng, Yuxia, et al.
Publicado: (2021)

d-ribose induces nephropathy through RAGE-dependent NF-κB inflammation
por: Hong, Jinni, et al.
Publicado: (2018)

1,2,3,4,6‑penta‑O‑galloyl‑β‑D‑glucose alleviates inflammation and oxidative stress in diabetic nephropathy rats through MAPK/NF‑κB and ERK/Nrf2/HO‑1 signaling pathways
por: Wang, Dong, et al.
Publicado: (2022)

PKCδ/MAPKs and NF-κB Pathways are Involved in the Regulation of Ingenane-Type Diterpenoids from Euphorbia neriifolia on Macrophage Function
por: Jiang, Mingyan, et al.
Publicado: (2021)

Curcumin Alleviates oxLDL Induced MMP-9 and EMMPRIN Expression through the Inhibition of NF-κB and MAPK Pathways in Macrophages
por: Cao, Jiatian, et al.
Publicado: (2017)

Xanthatin Alleviates LPS-Induced Inflammatory Response in RAW264.7 Macrophages by Inhibiting NF-κB, MAPK and STATs Activation
por: Liu, Yuanqi, et al.
Publicado: (2022)

Effects of andrographolide on postoperative cognitive dysfunction and the association with NF-κB/MAPK pathway
por: Ding, Yongbo, et al.
Publicado: (2017)

Calycosin Suppresses RANKL-Mediated Osteoclastogenesis through Inhibition of MAPKs and NF-κB
por: Quan, Gui-Hua, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_6mrk89fcovo3362602mvsnp6nl