Primary amelanotic malignant melanoma of the male urethra with inguinal lymph node metastasis successfully controlled by nivolumab: A case report

We report a rare case of primary amelanotic malignant melanoma of the male urethra. A 65-year-old man with a urethral mass was referred to our hospital. A pathological diagnosis of a biopsy specimen revealed malignant melanoma. Thereafter, the patient underwent partial penectomy. The histopathologic...

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Detalles Bibliográficos
Autores principales: Tokita, Takashi, Kawahara, Takashi, Ito, Yusuke, Tsutsumi, Sohgo, Abe, Koichi, Namura, Kazuhiro, Sano, Futoshi, Shioi, Koichi, Takamoto, Daiji, Yumura, Yasushi, Nakaigawa, Noboru, Yao, Masahiro, Uemura, Hiroji, Wada, Hidefumi, Tsuura, Yukio, Kobayashi, Kazuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958931/
https://www.ncbi.nlm.nih.gov/pubmed/29785370
http://dx.doi.org/10.1016/j.eucr.2018.03.006
Descripción
Sumario:We report a rare case of primary amelanotic malignant melanoma of the male urethra. A 65-year-old man with a urethral mass was referred to our hospital. A pathological diagnosis of a biopsy specimen revealed malignant melanoma. Thereafter, the patient underwent partial penectomy. The histopathological diagnosis was amelanotic malignant melanoma of the urethra. The patient had received DAV-Feron in an adjuvant setting; however, PET-CT revealed multiple metastasis. After receiving more than 10 cycles of nivolumab, the accumulation of FDG was no longer observed on PET-CT. The patient is currently free from recurrence at 20 months after nivolumab treatment.

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