Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators

The pathogenic fungus Cryptococcus neoformans exhibits morphological changes in cell size during lung infection, producing both typical size 5 to 7 μm cells and large titan cells (> 10 μm and up to 100 μm). We found and optimized in vitro conditions that produce titan cells in order to identify t...

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Detalles Bibliográficos
Autores principales: Hommel, Benjamin, Mukaremera, Liliane, Cordero, Radames J. B., Coelho, Carolina, Desjardins, Christopher A., Sturny-Leclère, Aude, Janbon, Guilhem, Perfect, John R., Fraser, James A., Casadevall, Arturo, Cuomo, Christina A., Dromer, Françoise, Nielsen, Kirsten, Alanio, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959062/
https://www.ncbi.nlm.nih.gov/pubmed/29775480
http://dx.doi.org/10.1371/journal.ppat.1006982

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