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Debate: Subgroup analyses in clinical trials: fun to look at - but don't believe them!
Analysis of subgroup results in a clinical trial is surprisingly unreliable, even in a large trial. This is the result of a combination of reduced statistical power, increased variance and the play of chance. Reliance on such analyses is likely to be more erroneous, and hence harmful, than applicati...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2000
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59592/ https://www.ncbi.nlm.nih.gov/pubmed/11714402 http://dx.doi.org/10.1186/cvm-1-1-025 |