A strategy utilizing ambulatory monitoring and home and clinic blood pressure measurements to optimize the safety evaluation of noncardiovascular drugs with potential for hemodynamic effects: a report from the SYNERGY trial

OBJECTIVE: The aim of this study was to perform a blood pressure (BP) safety evaluation in patients with an overactive bladder receiving solifenacin (an antimuscarinic agent), mirabegron (a β(3)-adrenoceptor agonist), or both compared with placebo in the SYNERGY trial. PATIENTS AND METHODS: Patients...

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Detalles Bibliográficos
Autores principales: Weber, Michael A., Chapple, Christopher R., Gratzke, Christian, Herschorn, Sender, Robinson, Dudley, Frankel, Jeffrey M., Ridder, Arwin M., Stoelzel, Matthias, Paireddy, Asha, van Maanen, Robert, White, William B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Analytical Methods and Statistical Analyses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959217/
https://www.ncbi.nlm.nih.gov/pubmed/29578880
http://dx.doi.org/10.1097/MBP.0000000000000320

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