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Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca(2+)–NFAT signaling

The metabolite acetyl-coenzyme A (acetyl-CoA) is the required acetyl donor for lysine acetylation and thereby links metabolism, signaling, and epigenetics. Nutrient availability alters acetyl-CoA levels in cancer cells, correlating with changes in global histone acetylation and gene expression. Howe...

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Detalles Bibliográficos
Autores principales:	Lee, Joyce V., Berry, Corbett T., Kim, Karla, Sen, Payel, Kim, Taehyong, Carrer, Alessandro, Trefely, Sophie, Zhao, Steven, Fernandez, Sully, Barney, Lauren E., Schwartz, Alyssa D., Peyton, Shelly R., Snyder, Nathaniel W., Berger, Shelley L., Freedman, Bruce D., Wellen, Kathryn E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959234/ https://www.ncbi.nlm.nih.gov/pubmed/29674394 http://dx.doi.org/10.1101/gad.311027.117

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