Repeat-mediated deletions can be induced by a chromosomal break far from a repeat, but multiple pathways suppress such rearrangements

Chromosomal deletion rearrangements mediated by repetitive elements often involve repeats separated by several kilobases and sequences that are divergent. While such rearrangements are likely induced by DNA double-strand breaks (DSBs), it has been unclear how the proximity of DSBs relative to repeat...

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Detalles Bibliográficos
Autores principales: Mendez-Dorantes, Carlos, Bhargava, Ragini, Stark, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959236/
https://www.ncbi.nlm.nih.gov/pubmed/29636371
http://dx.doi.org/10.1101/gad.311084.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959236/
https://www.ncbi.nlm.nih.gov/pubmed/29636371
http://dx.doi.org/10.1101/gad.311084.117

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