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White matter microstructure, white matter lesions, and hypertension: An examination of early surrogate markers of vascular-related brain change in midlife

OBJECTIVE: We examined imaging surrogates of white matter microstructural abnormalities which may precede white matter lesions (WML) and represent a relevant marker of cerebrovascular injury in adults in midlife. METHODS: In 698 community-dwelling adults (mean age 50 years ±3.5 SD) from the Coronary...

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Detalles Bibliográficos
Autores principales: Haight, Thaddeus, Nick Bryan, R., Erus, Guray, Hsieh, Meng-Kang, Davatzikos, Christos, Nasrallah, Ilya, D'Esposito, Mark, Jacobs, David R., Lewis, Cora, Schreiner, Pamela, Sidney, Stephen, Meirelles, Osorio, Launer, Lenore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959740/
https://www.ncbi.nlm.nih.gov/pubmed/29785359
http://dx.doi.org/10.1016/j.nicl.2018.02.032