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How Monte Carlo heuristics aid to identify the physical processes of drug release kinetics
We implement a Monte Carlo heuristic algorithm to model drug release from a solid dosage form. We show that with Monte Carlo simulations it is possible to identify and explain the causes of the unsatisfactory predictive power of current drug release models. It is well known that the power-law, the e...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959741/ https://www.ncbi.nlm.nih.gov/pubmed/29785391 http://dx.doi.org/10.1016/j.mex.2018.02.004 |