Determination of antioxidant and antimicrobial activities of leaf extracts of Otostegia integrifolia

BACKGROUND: The extracts from the leaves of Otostegia integrifolia have been reported to show phytochemical analysis, total flavonoid content, antioxidant and antibacterial activities. RESULTS: Our results revealed that the total flavonoid content of methanol and ethyl acetate extracts is 416.5 + 0....

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Detalles Bibliográficos
Autores principales: Chekol, Yiketel Adege, Desta, Zelalem Yibralign
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959825/
https://www.ncbi.nlm.nih.gov/pubmed/29777399
http://dx.doi.org/10.1186/s13065-018-0433-2
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author Chekol, Yiketel Adege
Desta, Zelalem Yibralign
author_facet Chekol, Yiketel Adege
Desta, Zelalem Yibralign
author_sort Chekol, Yiketel Adege
collection PubMed
description BACKGROUND: The extracts from the leaves of Otostegia integrifolia have been reported to show phytochemical analysis, total flavonoid content, antioxidant and antibacterial activities. RESULTS: Our results revealed that the total flavonoid content of methanol and ethyl acetate extracts is 416.5 + 0.288 and 248.9 + 0.872 mgAAE/100 g respectively. The two extracts also showed good antioxidant activity as well as weak to moderate antibacterial activity against some bacteria. CONCLUSIONS: The leaf extracts from O. integrifolia showed good total flavonoid content, DPPH radical scavenging activity and antibacterial activity. In addition to this, the extracts also showed the presence of some important compounds by phytochemical analysis.
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spelling pubmed-59598252018-06-14 Determination of antioxidant and antimicrobial activities of leaf extracts of Otostegia integrifolia Chekol, Yiketel Adege Desta, Zelalem Yibralign Chem Cent J Research Article BACKGROUND: The extracts from the leaves of Otostegia integrifolia have been reported to show phytochemical analysis, total flavonoid content, antioxidant and antibacterial activities. RESULTS: Our results revealed that the total flavonoid content of methanol and ethyl acetate extracts is 416.5 + 0.288 and 248.9 + 0.872 mgAAE/100 g respectively. The two extracts also showed good antioxidant activity as well as weak to moderate antibacterial activity against some bacteria. CONCLUSIONS: The leaf extracts from O. integrifolia showed good total flavonoid content, DPPH radical scavenging activity and antibacterial activity. In addition to this, the extracts also showed the presence of some important compounds by phytochemical analysis. Springer International Publishing 2018-05-18 /pmc/articles/PMC5959825/ /pubmed/29777399 http://dx.doi.org/10.1186/s13065-018-0433-2 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Chekol, Yiketel Adege
Desta, Zelalem Yibralign
Determination of antioxidant and antimicrobial activities of leaf extracts of Otostegia integrifolia
title Determination of antioxidant and antimicrobial activities of leaf extracts of Otostegia integrifolia
title_full Determination of antioxidant and antimicrobial activities of leaf extracts of Otostegia integrifolia
title_fullStr Determination of antioxidant and antimicrobial activities of leaf extracts of Otostegia integrifolia
title_full_unstemmed Determination of antioxidant and antimicrobial activities of leaf extracts of Otostegia integrifolia
title_short Determination of antioxidant and antimicrobial activities of leaf extracts of Otostegia integrifolia
title_sort determination of antioxidant and antimicrobial activities of leaf extracts of otostegia integrifolia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959825/
https://www.ncbi.nlm.nih.gov/pubmed/29777399
http://dx.doi.org/10.1186/s13065-018-0433-2
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