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Bacterial encapsulins as orthogonal compartments for mammalian cell engineering

We genetically controlled compartmentalization in eukaryotic cells by heterologous expression of bacterial encapsulin shell and cargo proteins to engineer enclosed enzymatic reactions and size-constrained metal biomineralization. The shell protein (EncA) from Myxococcus xanthus auto-assembles into n...

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Detalles Bibliográficos
Autores principales:	Sigmund, Felix, Massner, Christoph, Erdmann, Philipp, Stelzl, Anja, Rolbieski, Hannes, Desai, Mitul, Bricault, Sarah, Wörner, Tobias P., Snijder, Joost, Geerlof, Arie, Fuchs, Helmut, Hrabĕ de Angelis, Martin, Heck, Albert J. R., Jasanoff, Alan, Ntziachristos, Vasilis, Plitzko, Jürgen, Westmeyer, Gil G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959871/ https://www.ncbi.nlm.nih.gov/pubmed/29777103 http://dx.doi.org/10.1038/s41467-018-04227-3

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